Background The systemic inflammatory response post-SARS-CoV-2 infection increases pro-
inflammatory cytokine production, multi-organ damage, and mortality rates. Mast cells (MC) …

Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in severely ill
patients and the pathophysiology of disease is thought to be immune-mediated. Mast cells …

Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients who
are severely ill, and the pathophysiology of disease is thought to be immune mediated. Mast …

The immune response plays a critical role in the pathophysiology of SARS-CoV-2 infection
ranging from protection to tissue damage and all occur in the development of acute …

Background There is still insufficient knowledge with regard to the potential involvement of
mast cells (MCs) and their mediators in the pathology of coronavirus disease-2019 (COVID …

Objectives Hyper-inflammation caused by COVID-19 may be mediated by mast cell
activation (MCA) which has also been hypothesized to cause Long-COVID (LC) symptoms …

Abstract SARS-CoV-2 infection-induced hyper-inflammation links to the acute lung injury
and COVID-19 severity. Identifying the primary mediators that initiate the uncontrolled …

To the Editor, Fatal coronavirus disease 2019 (COVID-19) features inflammatory changes
affecting the whole lung with profound parenchymal destruction. Severe acute respiratory …

Abstract Objectives One-fifth of Covid-19 patients suffer a severe course of Covid-19
infection; however, the specific causes remain unclear. Mast cells (MCs) are activated by …

Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection represents a
global health crisis. Immune cell activation via pattern recognition receptors has been …