TRIM21 (Ro52/SSA1) is an E3 ubiquitin ligase with key roles in immune host defence, signal
transduction, and possibly cell cycle regulation. It is also an autoantibody target in Sjögren's …

TRIM21 is one of the autoantigens that reacts with an anti-SS-A antibody (Ab) present in
patients with systemic lupus erythematosus (SLE) and Sjögren's syndrome. TRIM21 is …

Ro52 is a common target of circulating autoantibodies in autoimmune disease. Data indicate
that anti-Ro52 antibodies are associated with distinct clinical manifestations. It is therefore of …

Systemic lupus erythematosus (SLE) is a chronic, systemic, and autoimmune disease,
whose etiology is still unknown. Although there has been progress in the treatment of SLE …

Tripartite motif-containing protein 21 (TRIM21) is a cytosolic antibody receptor and E3
ubiquitin ligase that promotes destruction of a broad range of pathogens. TRIM21 also …

Tripartite motif (TRIM) 21 is a cytosolic antibody receptor that neutralizes antibody-coated
viruses that penetrate the cell and simultaneously activates innate immunity. Here we show …

The tripartite motif-containing (TRIM) proteins represent the largest E3 ubiquitin ligase
family. The multifaceted roles of TRIM38 in innate immunity and inflammation have been …

Tripartite motif containing-21 (TRIM21), an E3 ubiquitin ligase, was initially found to be
involved in antiviral responses and autoimmune diseases. Recently studies have reported …

The tripartite motif (TRIM) proteins have been intensively studied as essential modulators in
various biological processes, especially in regulating a wide range of signaling pathways …

Tripartite motif (TRIM) family proteins, most of which have E3 ubiquitin ligase activities, have
various functions in cellular processes including intracellular signaling, development …