Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial

HC Gerstein, HM Colhoun, GR Dagenais, R Diaz… - The Lancet, 2019 - thelancet.com
Background Three different glucagon-like peptide-1 (GLP-1) receptor agonists reduce
cardiovascular outcomes in people with type 2 diabetes at high cardiovascular risk with high …

Cardiovascular safety for once-weekly dulaglutide in type 2 diabetes: a pre-specified meta-analysis of prospectively adjudicated cardiovascular events

KC Ferdinand, FT Botros, CM Atisso… - Cardiovascular diabetology, 2016 - Springer
Background Patients with type 2 diabetes (T2D) have a substantial increased risk for
cardiovascular (CV) disease and associated mortality than those without diabetes …

Exploring potential mediators of the cardiovascular benefit of dulaglutide in type 2 diabetes patients in REWIND

M Konig, MC Riddle, HM Colhoun, KR Branch… - Cardiovascular …, 2021 - Springer
Background The REWIND trial demonstrated cardiovascular (CV) benefits to patients with
type 2 diabetes and multiple CV risk factors or established CV disease. This exploratory …

Dulaglutide and renal outcomes in type 2 diabetes: an exploratory analysis of the REWIND randomised, placebo-controlled trial

HC Gerstein, HM Colhoun, GR Dagenais, R Diaz… - The Lancet, 2019 - thelancet.com
Background Two glucagon-like peptide-1 (GLP-1) receptor agonists reduced renal
outcomes in people with type 2 diabetes at risk for cardiovascular disease. We assessed the …

The effect of dulaglutide on stroke: an exploratory analysis of the REWIND trial

HC Gerstein, R Hart, HM Colhoun, R Diaz… - The Lancet Diabetes & …, 2020 - thelancet.com
Background Cardiovascular outcome trials have suggested that glucagon-like peptide 1
(GLP-1) receptor agonists might reduce strokes. We analysed the effect of dulaglutide on …

Effect of once‐weekly dulaglutide on glycated haemoglobin (HbA1c) and fasting blood glucose in patient subpopulations by gender, duration of diabetes and baseline …

B Gallwitz, S Dagogo‐Jack, V Thieu… - Diabetes, Obesity …, 2018 - Wiley Online Library
Aims To evaluate the efficacy and safety of dulaglutide 1.5 and 0.75 mg in patients with type
2 diabetes by subgroups of gender, duration of diabetes and baseline glycated …

LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled …

S Urva, T Coskun, MT Loh, Y Du, MK Thomas… - The Lancet, 2022 - thelancet.com
Background Treating hyperglycaemia and obesity in individuals with type 2 diabetes using
multi-receptor agonists can improve short-term and long-term outcomes. LY3437943 is a …

Monotherapy with the once‐weekly GLP‐1 analogue dulaglutide for 12 weeks in patients with type 2 diabetes: dose‐dependent effects on glycaemic control in a …

G Grunberger, A Chang, G Garcia Soria… - Diabetic …, 2012 - Wiley Online Library
Diabet. Med. 29, 1260–1267 (2012) Abstract Aims Evaluate dose‐dependent effects of once‐
weekly dulaglutide, a glucagon‐like peptide‐1 analogue, on glycaemic control in patients …

Efficacy and safety of dulaglutide monotherapy versus metformin in type 2 diabetes in a randomized controlled trial (AWARD-3)

G Umpierrez, S Tofé Povedano, F Pérez Manghi… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE Compare the efficacy and safety of monotherapy with dulaglutide, a once-
weekly GLP-1 receptor agonist, to metformin-treated patients with type 2 diabetes. The …

Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): a 24-week, randomised, double-blind …

B Ludvik, JP Frías, FJ Tinahones… - The lancet Diabetes & …, 2018 - thelancet.com
Summary Background Glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-
glucose co-transporter-2 (SGLT2) inhibitors improve glycaemic control and reduce …