Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease

F Crispi, J Miranda, E Gratacós - American journal of obstetrics and …, 2018 - Elsevier
In the modern world, cardiovascular disease is a leading cause of death for both men and
women. Epidemiologic studies consistently have suggested an association between low …

[HTML][HTML] Fetal programming and cardiovascular pathology

BT Alexander, JH Dasinger… - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Low birth weight serves as a crude proxy for impaired growth during fetal life and indicates a
failure for the fetus to achieve its full growth potential. Low birth weight can occur in …

Intrauterine growth restriction: impact on cardiovascular development and function throughout infancy

E Cohen, FY Wong, RSC Horne, SR Yiallourou - Pediatric research, 2016 - nature.com
Intrauterine growth restriction (IUGR) refers to the situation where a fetus does not grow
according to its genetic growth potential. One of the main causes of IUGR is uteroplacental …

Fetal growth restriction results in remodeled and less efficient hearts in children

F Crispi, B Bijnens, F Figueras, J Bartrons, E Eixarch… - Circulation, 2010 - Am Heart Assoc
Background—Fetal growth restriction (FGR) affects 5% to 10% of newborns and is
associated with increased cardiovascular mortality in adulthood. The most commonly …

Adult consequences of fetal growth restriction

DJP Barker - Clinical obstetrics and gynecology, 2006 - journals.lww.com
Low birthweight in relation to the length of gestation, is now known to be associated with
increased rates of coronary heart disease and the related disorders stroke, hypertension …

Neonatal and long-term consequences of fetal growth restriction

M Colella, A Frérot, ARB Novais… - Current pediatric …, 2018 - ingentaconnect.com
Background: Fetal Growth Restriction (FGR) is one of the most common noxious antenatal
conditions in humans, inducing a substantial proportion of preterm delivery and leading to a …

Neonatal morbidities of fetal growth restriction: pathophysiology and impact

A Malhotra, BJ Allison, M Castillo-Melendez… - Frontiers in …, 2019 - frontiersin.org
Being born small lays the foundation for short-term and long-term implications for life.
Intrauterine or fetal growth restriction describes the pregnancy complication of pathological …

Long-term follow-up of intrauterine growth restriction: cardiovascular disorders

E Demicheva, F Crispi - Fetal diagnosis and therapy, 2014 - karger.com
In the modern world, cardiovascular disorders are the leading cause of mortality in
developed countries, which in most cases undergo a long subclinical phase that can last …

Persistence of cardiac remodeling in preadolescents with fetal growth restriction

SI Sarvari, M Rodriguez-Lopez… - Circulation …, 2017 - Am Heart Assoc
Background—Fetal growth restriction (FGR) affects 5% to 10% of newborns and is
associated with increased cardiovascular mortality in adulthood. We evaluated whether …

[PDF][PDF] Hypoxia or nutrient restriction during pregnancy in rats leads to progressive cardiac remodeling and impairs postischemic recovery in adult male offspring

Y Xu, SJ Williams, D O'brien, ST Davidge, Y Xu… - The FASEB …, 2006 - researchgate.net
A series of epidemiological studies have demonstrated that intrauterine growth restriction
(IUGR) is associated with an increased risk of developing cardiovascular disease in adult …