Introduction Periodontitis-related oral microbial dysbiosis is thought to contribute to
Alzheimer's disease (AD) neuroinflammation and brain amyloid production. Since probiotics …

The oral cavity is the initial chamber of digestive tract; the saliva swallowed daily contains an
estimated 1.5× 1012 oral bacteria. Increasing evidence indicates that periodontal pathogens …

Porphyromonas gingivalis is a gram-negative bacterium found in the human oral cavity and
is responsible for the development of chronic periodontitis as well as neurological diseases …

Although epidemiological studies suggest that periodontitis is tightly associated with
ischemic stroke, its impact on ischemic stroke and the underlysing mechanisms are poorly …

Dysbiosis of the oral microbiome mediates chronic periodontal disease. Realignment of
microbial dysbiosis towards health may prevent disease. Treatment with antibiotics and …

Background Periodontal pathogen and gut microbiota are closely associated with the
pathogenesis of Alzheimer's disease (AD). Porphyromonas gingivalis (Pg), the keystone …

Periodontitis is a dysbiotic infectious disease that leads to the destruction of tooth supporting
tissues. There is increasing evidence that periodontitis may affect the development and …

Mechanisms linking intestinal bacteria and neurodegenerative diseases such as
Alzheimer's disease (AD) are still unclear. We hypothesized that intestinal dysbiosis might …

Aim Periodontitis is caused by dysbiosis of oral microbes and is associated with increased
cognitive decline in Alzheimer's disease (AD), and recently, a potential functional link was …

Periodontitis, a chronic, inflammatory disease, induces systemic inflammation and
contributes to the development of neurodegenerative diseases. The precise etiology of the …