Over the last few years disintegrin metalloproteinases of the Adam (a disintegrin and
metalloproteinase) family have been associated with the process of proteolytic'shedding'of …

A disintegrin and metalloproteinases (ADAMs) are a recently discovered family of proteins
that share the metalloproteinase domain with matrix metalloproteinases (MMPs). Among this …

The ADAMs (a disintegrin and metalloproteinase) comprise a family of multidomain
transmembrane and secreted proteins. One of their best-established roles is the release of …

The ADAMs (a disintegrin and metalloproteases) are transmembrane multidomain proteins
implicated in multiple biological processes including proteolysis, cell adhesion, cell fusion …

Members of the ADAM (a disintegrin and metalloproteinase) family of proteolytic enzymes
are implicated in the processing of many single transmembrane-bound proteins ranging …

Both cancer and chronic inflammatory diseases are often marked by homeostatic signal
transduction pathways run amok. Cleavage of membrane-bound substrates by extracellular …

Ectodomain shedding of extracellular and membrane proteins is of fundamental importance
for cell–cell communication in neoplasias. A Disintegrin And Metalloproteinase (ADAM) …

Background A disintegrin and metalloproteinase-12 (ADAM12) is a member of the greater
ADAM family of enzymes: these are multifunctional, generally membrane-bound, zinc …

Publisher Summary Since their discovery about a decade ago, some very intriguing insights
into the function of a few Anchored Metalloprotease-Disintegrin Proteins (ADAMs) have …

ADAM (a disintegrin and metalloprotease) proteins are membrane-anchored
metalloproteases that process and shed the ectodomains of membrane-anchored growth …