Cellular differentiation is one of the critical processes in the life of multicellular organisms. In
this phenomenon, a non-specialized cell is converted to a specialized one with its own …

Caspases are proteolytic enzymes that belong to the cysteine protease family and play a
crucial role in homeostasis and programmed cell death. Caspases have been broadly …

Caspases are a family of cysteine proteases, and the key factors behind the cellular events
which occur during apoptosis and inflammation. However, increasing evidence shows the …

While in multicellular organisms all cells inexorably die, there are several different ways
provided for the realization of cell death. One of them, apoptosis, represents a universal …

Intricate networks of protein kinases are intimately involved in the regulation of cellular
events related to cell proliferation and survival. In addition to protein kinases, cells also …

The number of scientific papers devoted to the study of caspases has lately being constantly
growing. Caspases are a family of cysteine-dependent aspartate specific proteases …

Apoptosis is the regulated form of cell death utilized by metazoans to remove unneeded,
damaged, or potentially deleterious cells. Certain manifestations of apoptosis may be …

Caspases are the terminal proteases involved in apoptosis, as well as being involved in
inflammation. The apoptotic caspases can be classified as either initiator or effector …

1. Apoptosis is an essential process to remove excess, unwanted and harmful cells and
maintain homeostasis. One of the key steps in apoptosis is activation of a group of proteases …

Objectives Cell proliferation and apoptosis play a major role in maintaining homeostasis and
as such any disruption within these processes can lead to disease states. Apoptosis occurs …