Impact of empirical antibiotic regimens on mortality in neutropenic patients with bloodstream infection presenting with septic shock
M Chumbita, P Puerta-Alcalde, C Gudiol… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
We analyzed risk factors for mortality in febrile neutropenic patients with bloodstream
infections (BSI) presenting with septic shock and assessed the impact of empirical antibiotic …
infections (BSI) presenting with septic shock and assessed the impact of empirical antibiotic …
Antibiotic treatment with one single dose of gentamicin at admittance in addition to a β-lactam antibiotic in the treatment of community-acquired bloodstream infection …
K Liljedahl Prytz, M Prag, H Fredlund, A Magnuson… - PLoS …, 2020 - journals.plos.org
Background Combination therapy in the treatment of sepsis, especially the value of
combining a β-Lactam antibiotic with an aminoglycoside, has been discussed. This …
combining a β-Lactam antibiotic with an aminoglycoside, has been discussed. This …
Risk factors and pathogenic significance of severe sepsis and septic shock in 2286 patients with gram-negative bacteremia
BACKGROUND: The aim of this study was to identify risk factors for development of severe
sepsis or septic shock and to evaluate the clinical impact of severe sepsis on outcome in …
sepsis or septic shock and to evaluate the clinical impact of severe sepsis on outcome in …
Impact of inadequate empirical therapy on the mortality of patients with bloodstream infections: a propensity score-based analysis
P Retamar, MM Portillo, MD López-Prieto… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The impact of the adequacy of empirical therapy on outcome for patients with bloodstream
infections (BSI) is key for determining whether adequate empirical coverage should be …
infections (BSI) is key for determining whether adequate empirical coverage should be …
Outcomes of nosocomial bloodstream infections in adult neutropenic patients: a prospective cohort and matched case-control study
H Wisplinghoff, OA Cornely, S Moser… - Infection Control & …, 2003 - cambridge.org
Objective: To examine the clinical and epidemiologic features, excess length of stay, extra
costs, and mortality attributable to bloodstream infection (BSI) in neutropenic patients with …
costs, and mortality attributable to bloodstream infection (BSI) in neutropenic patients with …
Factors associated with severe sepsis: prospective study of 94 neutropenic febrile episodes
R Jeddi, M Achour, RB Amor, L Aissaoui, W Bouterâa… - …, 2010 - Taylor & Francis
Severe sepsis defined as infection-induced organ dysfunction or hypoperfusion
abnormalities predispose to septic shock and increased mortality in neutropenic setting. We …
abnormalities predispose to septic shock and increased mortality in neutropenic setting. We …
Community-acquired bloodstream infection in critically ill adult patients: impact of shock and inappropriate antibiotic therapy on survival
J Valles, J Rello, A Ochagavía, J Garnacho, MA Alcalá - Chest, 2003 - Elsevier
Design: The objectives were to characterize the prognostic factors and evaluate the impact
of inappropriate empiric antibiotic treatment and systemic response on the outcome of …
of inappropriate empiric antibiotic treatment and systemic response on the outcome of …
De-escalation of antimicrobial treatment in neutropenic patients with severe sepsis: results from an observational study
D Mokart, G Slehofer, J Lambert, A Sannini… - Intensive care …, 2014 - Springer
Background In severe sepsis, guidelines recommend de-escalating the empirical
antimicrobial treatment as soon as the microbiological results are available. We aimed to …
antimicrobial treatment as soon as the microbiological results are available. We aimed to …
Short-course adjunctive gentamicin as empirical therapy in patients with severe sepsis and septic shock: a prospective observational cohort study
DSY Ong, JF Frencken… - Clinical Infectious …, 2017 - academic.oup.com
Background. Metaanalyses failed to demonstrate clinical benefits of beta lactam plus
aminoglycoside combination therapy compared to beta lactam monotherapy in patients with …
aminoglycoside combination therapy compared to beta lactam monotherapy in patients with …
Inappropriate empirical antibiotic treatment in high-risk neutropenic patients with bacteremia in the era of multidrug resistance
G Martinez-Nadal, P Puerta-Alcalde… - Clinical Infectious …, 2020 - academic.oup.com
Background We aimed to describe the current rates of inappropriate empirical antibiotic
treatment (IEAT) in oncohematological patients with febrile neutropenia (FN) and its impact …
treatment (IEAT) in oncohematological patients with febrile neutropenia (FN) and its impact …
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