Pyridine-based ring systems are one of the most extensively used heterocycles in the field of
drug design, primarily due to their profound effect on pharmacological activity, which has led …

The nitrogen-bearing heterocycle pyridine in its several analogous forms occupies an
important position as a precious source of clinically useful agents in the field of medicinal …

2-Aminopyridine is a simple, low molecular weight and perfectly functionalised moiety
known for the synthesis of diverse biological molecules. Many pharmaceutical companies …

1, 4-Dihydropyridines were introduced in the last century for the treatment of coronary
diseases. Then medicinal chemists decorated the 1, 4-DHP nucleus, the most studied …

Pyridones have been utilized as privileged scaffolds in drug discovery. Some of the
important roles where this class of heterocycles have found utility in medicinal chemistry …

Fused heterocycles are reported to demonstrate variety of biological activities such as
anticancer, antibacterial, antifungal and anti-inflammatory, and are thus exhaustively utilized …

Background The chemistry and applications of 2-pyridone structures have recently attracted
a lot of attention due to their uses as synthetic intermediates and their biological importance …

The interest in pyridopyrimidine cores for pharmaceutical products makes this scaffold a
highly useful building block for organic chemistry. These derivatives have found applications …

The pyrimidine scaffold represents an important pharmacophore endowed with a wide
range of pharmacological activities according to the specific decoration of the heterocycle …

Dihydropyridine (DHP) is among the most beneficial scaffolds that have revolutionised
pharmaceutical research with unprecedented biological properties. Over the years …