Background: Although knowledge of the genetic factors influencing kidney disease is
increasing, epigenetic profiles, which are associated with chronic kidney disease (CKD) …

Since the etiology of diabetic chronic kidney disease (CKD) is multifactorial, studies on DNA
methylation for kidney function deterioration have rarely been performed despite the need …

Genetic risk factors for chronic kidney disease (CKD) are being identified through
international collaborations. By comparison, epigenetic risk factors for CKD have only …

Chronic kidney disease (CKD) is defined by reduced estimated glomerular filtration rate
(eGFR). Previous genetic studies have implicated regulatory mechanisms contributing to …

Background Older patients are at risk for acute kidney injury and chronic kidney disease.
Age-related increases in DNA methylation at CpG islands have been linked to aging-related …

Background Epigenetic mechanisms may be important in the progression of chronic kidney
disease (CKD). Methods We studied the genome-wide DNA methylation pattern associated …

Background We investigated a cross-sectional epigenome-wide association study of
patients with early and late diabetes-associated chronic kidney disease (CKD) to identify …

Type 1 diabetes affects over nine million individuals globally, with approximately 40%
developing diabetic kidney disease. Emerging evidence suggests that epigenetic …

Background A subset of individuals with type 1 diabetes mellitus (T1DM) are predisposed to
developing diabetic kidney disease (DKD), the most common cause globally of end-stage …

Epigenetic markers are potential biomarkers for diabetes and related complications. Using a
prospective cohort from the Hong Kong Diabetes Register, we perform two independent …