Reovirus infection is initiated by interactions between the attachment protein σ1 and cell
surface carbohydrate and junctional adhesion molecule A (JAM-A). Expression of a JAM-A …

Reovirus cell entry is mediated by attachment to cell surface carbohydrate and junctional
adhesion molecule A (JAM-A) and internalization by β1 integrin. The β1 integrin cytoplasmic …

Reovirus infection requires the concerted action of viral and host factors to promote cell
entry. After interaction of reovirus attachment protein σ1 with cell-surface carbohydrates and …

Reovirus infections are initiated by the binding of viral attachment protein σ1 to receptors on
the surface of host cells. The σ1 protein is an elongated fiber comprised of an N-terminal tail …

Reovirus cell entry is initiated by viral attachment to cell surface glycans and junctional
adhesion molecule A. Following receptor engagement, reovirus is internalized into cells by …

Viral attachment to specific host receptors is the first step in viral infection and serves an
essential function in the selection of target cells. Mammalian reoviruses are highly useful …

Junctional adhesion molecule-A (JAM-A) serves as a serotype-independent receptor for
mammalian orthoreoviruses (reoviruses). The membrane-distal immunoglobulin-like D1 …

Reovirus attachment to cells is mediated by the binding of viral attachment protein σ1 to
junctional adhesion molecule 1 (JAM1). The crystal structure of the extracellular region of …

Mammalian orthoreoviruses (reoviruses) are prototype members of the Reoviridae family of
nonenveloped viruses. Reoviruses contain ten double-stranded RNA gene segments …

Diverse families of viruses bind immunoglobulin superfamily (IgSF) proteins located in tight
junctions (TJs) and adherens junctions of epithelium and endothelium. However, little is …