A feature-based analysis identifies COL1A2 as a regulator in pancreatic cancer

J Wu, J Liu, XQ Wei, Q Yu, XH Niu… - Journal of enzyme …, 2019 - Taylor & Francis
This study aimed to identify genetic biomarkers in pancreatic cancer (PC) and explore its
function in PC via a feature-base analysis of bioinformatics. OMIM and DisGeNET databases …

[HTML][HTML] RUNX2 and LAMC2: promising pancreatic cancer biomarkers identified by an integrative data mining of pancreatic adenocarcinoma tissues

G Jin, Q Ruan, F Shangguan, L Lan - Aging (albany NY), 2021 - ncbi.nlm.nih.gov
Pancreatic carcinoma (PC) is a severe disease associated with high mortality. Although
strategies for cancer therapy have made great progress, outcomes of pancreatic carcinoma …

[HTML][HTML] Key genes associated with pancreatic cancer and their association with outcomes: A bioinformatics analysis

J Wu, Z Li, K Zeng, K Wu, D Xu… - Molecular medicine …, 2019 - spandidos-publications.com
Pancreatic cancer is a highly malignant neoplastic disease of the digestive system. In the
present study, the dataset GSE62165 was downloaded from the Gene Expression Omnibus …

[HTML][HTML] Identification of novel therapeutic target genes and pathway in pancreatic cancer by integrative analysis

B Hu, C Shi, H Jiang, S Qin - Medicine, 2017 - journals.lww.com
Background: Gene alterations are crucial to the molecular pathogenesis of pancreatic
cancer. The present study was designed to identify the potential candidate genes in the …

[HTML][HTML] Identification of key genes and pathways in pancreatic cancer gene expression profile by integrative analysis

W Lu, N Li, F Liao - Genes, 2019 - mdpi.com
Background: Pancreatic cancer is one of the malignant tumors that threaten human health.
Methods: The gene expression profiles of GSE15471, GSE19650, GSE32676 and …

[HTML][HTML] COL12A1 acts as a novel prognosis biomarker and activates cancer-associated fibroblasts in pancreatic cancer through bioinformatics and experimental …

Y Song, L Wang, K Wang, Y Lu, P Zhou - Cancers, 2023 - mdpi.com
Simple Summary Cancer-associated fibroblasts (CAFs) are key stromal cells in the tumor
microenvironment (TME) that play a crucial role in tumor progression in pancreatic cancer …

[HTML][HTML] Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics …

J Ding, Y Liu, Y Lai - PeerJ, 2020 - peerj.com
Background Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant neoplasm. It is
necessary to improve the understanding of the underlying molecular mechanisms and …

[HTML][HTML] Identification of molecular biomarkers for pancreatic cancer with mRMR shortest path method

S Shen, T Gui, C Ma - Oncotarget, 2017 - ncbi.nlm.nih.gov
The high mortality rate of pancreatic cancer makes it one of the most studied diseases
among all cancer types. Many researches have been conducted to understand the …

Combining bioinformatics techniques to explore the molecular mechanisms involved in pancreatic cancer metastasis and prognosis

JS Xu, K Liao, X Wang, J He… - Journal of Cellular and …, 2020 - Wiley Online Library
This article aims to explore the underlying molecular mechanisms and prognosis‐related
genes in pancreatic cancer metastasis. Pancreatic cancer metastasis‐related gene chip …

RETRACTED ARTICLE: A comprehensive analysis of candidate genes and pathways in pancreatic cancer

J Liu, J Li, H Li, A Li, B Liu, L Han - Tumor Biology, 2015 - Springer
The study aimed to dissect the molecular mechanism of pancreatic cancer by a range of
bioinformatics approaches. Three microarray datasets (GSE32676, GSE21654, and …