[HTML][HTML] The dorsolateral prefrontal cortex in acute and chronic pain

DA Seminowicz, M Moayedi - The journal of pain, 2017 - Elsevier
The dorsolateral prefrontal cortex (DLPFC) is a functionally and structurally heterogeneous
region and a key node of several brain networks, implicated in cognitive, affective, and …

Keeping pain out of mind: the role of the dorsolateral prefrontal cortex in pain modulation

J Lorenz, S Minoshima, KL Casey - Brain, 2003 - academic.oup.com
Frontal lobe activity during pain is generally linked to attentional processing. We addressed
the question of whether 'bottom‐up'processing and 'top‐down'modulation of nociceptive …

Hemispheric dorsolateral prefrontal cortex lateralization in the regulation of empathy for pain

GG Rêgo, OM Lapenta, LM Marques, TL Costa… - Neuroscience …, 2015 - Elsevier
The dorsolateral prefrontal cortex (DLPFC) is involved in the cognitive appraisal and
modulation of the pain experience. In this sham-controlled study, with healthy volunteers, we …

dmPFC-vlPAG projection neurons contribute to pain threshold maintenance and antianxiety behaviors

JB Yin, SH Liang, F Li, WJ Zhao, Y Bai… - The Journal of …, 2020 - Am Soc Clin Investig
The dorsal medial prefrontal cortex (dmPFC) has been recognized as a key cortical area for
nociceptive modulation. However, the underlying neural pathway and the function of specific …

Repetitive transcranial magnetic stimulation of dorsolateral prefrontal cortex increases tolerance to human experimental pain

A Graff-Guerrero, J González-Olvera, A Fresán… - Cognitive Brain …, 2005 - Elsevier
Dorsolateral prefrontal cortex (DLPFCx) has been implicated in pain perception and in a
pain modulation pathway. However, the precise participation of this region is not completely …

[HTML][HTML] High-frequency rTMS over the dorsolateral prefrontal cortex on chronic and provoked pain: A systematic review and meta-analysis

X Che, RFH Cash, X Luo, H Luo, X Lu, F Xu, YF Zang… - Brain stimulation, 2021 - Elsevier
Background High-frequency rTMS over the dorsolateral prefrontal cortex (DLPFC) has
demonstrated mixed effects on chronic and provoked pain. Objectives/Methods In this study …

Influence of transcranial direct current stimulation of the dorsolateral prefrontal cortex on pain related emotions: a study using electroencephalographic power …

H Maeoka, A Matsuo, M Hiyamizu, S Morioka… - Neuroscience letters, 2012 - Elsevier
Pain is a multidimensional experience with sensory-discriminative, cognitive-evaluative and
affective-motivational components. Emotional factors such as unpleasantness or anxiety are …

Abnormal medial prefrontal cortex functional connectivity and its association with clinical symptoms in chronic low back pain

Y Tu, M Jung, RL Gollub, V Napadow, J Gerber, A Ortiz… - Pain, 2019 - journals.lww.com
Accumulating evidence has shown that complicated brain systems are involved in the
development and maintenance of chronic low back pain (cLBP), but the association …

The medial prefrontal cortex as a central hub for mental comorbidities associated with chronic pain

KK Kummer, M Mitrić, T Kalpachidou… - International journal of …, 2020 - mdpi.com
Chronic pain patients frequently develop and suffer from mental comorbidities such as
depressive mood, impaired cognition, and other significant constraints of daily life, which …

Role of the prefrontal cortex in pain processing

WY Ong, CS Stohler, DR Herr - Molecular neurobiology, 2019 - Springer
The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral …