A number of mechanisms ensure that the intestine is protected from pathogens and also
against our own intestinal microbiota. The outermost of these is the secreted mucus, which …

The gastrointestinal tract is covered by mucus that has different properties in the stomach,
small intestine, and colon. The large highly glycosylated gel‐forming mucins MUC 2 and …

The gastrointestinal tract is coated by a thick layer of mucus that forms the front line of innate
host defense. Mucus consists of high molecular weight glycoproteins called mucins that are …

Goblet cells and the mucus they secrete serve as an important barrier, preventing pathogens
from invading the mucosa to cause intestinal inflammation. The perspective regarding goblet …

Goblet cells and their main secretory product, mucus, have long been poorly appreciated;
however, recent discoveries have changed this and placed these cells at the center stage of …

Throughout the gastrointestinal (GI) tract, a distinct mucus layer composed of highly
glycosylated proteins called mucins plays an essential role in providing lubrication for the …

Goblet cells reside throughout the gastrointestinal (GI) tract and are responsible for the
production and preservation of a protective mucus blanket by synthesizing and secreting …

Mucins—large, highly glycosylated proteins—are important for the luminal protection of the
gastrointestinal tract. Enterocytes have their apical surface covered by transmembrane …

The intestinal tract faces numerous challenges that require several layers of defence. The
tight epithelium forms a physical barrier that is further protected by a mucus layer, which …

The intestinal epithelium is covered with mucus with the main structural building block being
the densely O-glycosylated MUC2 mucin. The intestinal epithelium is exposed to ingested …