[PDF][PDF] Cordycepin ameliorates nonalcoholic steatohepatitis by activation of the AMP‐activated protein kinase signaling pathway

T Lan, Y Yu, J Zhang, H Li, Q Weng, S Jiang… - …, 2021 - Wiley Online Library
Background and Aims Nonalcoholic fatty liver disease, especially nonalcoholic
steatohepatitis (NASH), has become a major cause of liver transplantation and liver …

Activation of AMPK by triptolide alleviates nonalcoholic fatty liver disease by improving hepatic lipid metabolism, inflammation and fibrosis

R Huang, F Guo, Y Li, Y Liang, G Li, P Fu, L Ma - Phytomedicine, 2021 - Elsevier
Background Triptolide is naturally isolated from Tripterygium wilfordii Hook F., possessing
multiple biological activities. Hepatotoxicity is one of the main side effects of triptolide …

Demethyleneberberine attenuates non-alcoholic fatty liver disease with activation of AMPK and inhibition of oxidative stress

X Qiang, L Xu, M Zhang, P Zhang, Y Wang… - Biochemical and …, 2016 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has reached an epidemic level globally, which is
recognized to form non-alcoholic steatohepatitis (NASH) by the “two-hit” model, including …

Scoparone alleviates inflammation, apoptosis and fibrosis of non-alcoholic steatohepatitis by suppressing the TLR4/NF-κB signaling pathway in mice

B Liu, X Deng, Q Jiang, G Li, J Zhang, N Zhang… - International …, 2019 - Elsevier
Scoparone, a naturally-occurring, bioactive compound isolated from the Chinese herb
Artemisia capillaria, has been shown to ameliorate hepatotoxicity and cholestasis in liver …

Protective effects of licochalcone A ameliorates obesity and non-alcoholic fatty liver disease via promotion of the Sirt-1/AMPK pathway in mice fed a high-fat diet

CJ Liou, YK Lee, NC Ting, YL Chen, SC Shen, SJ Wu… - Cells, 2019 - mdpi.com
Licochalcone A is a chalcone isolated from Glycyrrhiza uralensis. It showed anti-tumor and
anti-inflammatory properties in mice with acute lung injuries and regulated lipid metabolism …

Salidroside activates the AMP‐activated protein kinase pathway to suppress nonalcoholic steatohepatitis in mice

M Hu, D Zhang, H Xu, Y Zhang, H Shi, X Huang… - …, 2021 - Wiley Online Library
Background and Aims NASH is becoming a leading cause of liver cirrhosis and HCC.
Salidroside (p‐hydroxyphenethyl‐β‐D‐glucoside; SAL) has various biological and …

Gastrodin improves nonalcoholic fatty liver disease through activation of the adenosine monophosphate–activated protein kinase signaling pathway

J Wan, Y Zhang, D Yang, Y Liang, L Yang, S Hu… - …, 2021 - Wiley Online Library
Background and Aims NASH is currently one of the most common causes of liver
transplantation and hepatocellular carcinoma. Thus far, there is still no effective …

Corosolic acid ameliorates non‐alcoholic steatohepatitis induced by high‐fat diet and carbon tetrachloride by regulating TGF‐β1/Smad2, NF‐κB, and AMPK signaling …

G Liu, Z Cui, X Gao, H Liu, L Wang, J Gong… - Phytotherapy …, 2021 - Wiley Online Library
Hawthorn (Crataegus pinnatifida Bunge. var. major) is an edible and medicinal fruit that is
very common in food and traditional Chinese medicine. Corosolic acid (CA), a pentacyclic …

Upregulation of SIRT1-AMPK by thymoquinone in hepatic stellate cells ameliorates liver injury

Y Yang, T Bai, YL Yao, DQ Zhang, YL Wu, LH Lian… - Toxicology letters, 2016 - Elsevier
Thymoquinone (TQ) is a biologically active compound isolated from the seeds of Nigella
sativa L.(Ranuculaceae). This study investigated the hepato-protective effect of TQ on liver …

Gastrodin ameliorates oxidative stress and proinflammatory response in nonalcoholic fatty liver disease through the AMPK/Nrf2 pathway

LL Qu, B Yu, Z Li, WX Jiang, JD Jiang… - Phytotherapy …, 2016 - Wiley Online Library
This study was designed to investigate the antioxidative, antiinflammatory and metabolism‐
regulating effects of gastrodin (GSTD) in the treatment of nonalcoholic fatty liver disease …