[HTML][HTML] Differential transcriptional responses to Ebola and Marburg virus infection in bat and human cells

M Hölzer, V Krähling, F Amman, E Barth, SH Bernhart… - Scientific reports, 2016 - nature.com
The unprecedented outbreak of Ebola in West Africa resulted in over 28,000 cases and
11,000 deaths, underlining the need for a better understanding of the biology of this highly …

Ebola and Marburg viruses: pathogenesis and development of countermeasures

LE Hensley, SM Jones, H Feldmann… - Current molecular …, 2005 - ingentaconnect.com
Ebola and Marburg viruses, family Filoviridae, are among the best known examples of
emerging and re-emerging pathogens. Although outbreaks have been sporadic and …

Global suppression of the host antiviral response by Ebola-and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced …

JC Kash, E Mühlberger, V Carter, M Grosch… - Journal of …, 2006 - Am Soc Microbiol
We studied the effect of filovirus infection on host cell gene expression by characterizing the
regulation of gene expression responses in human liver cells infected with Zaire Ebolavirus …

[HTML][HTML] Transcriptional analysis of viral mRNAs reveals common transcription patterns in cells infected by five different filoviruses

CG Albariño, L Wiggleton Guerrero, AK Chakrabarti… - PLoS …, 2018 - journals.plos.org
Filoviruses are notorious viral pathogens responsible for high-consequence diseases in
humans and non-human primates. Transcription of filovirus mRNA shares several common …

Filovirus pathogenesis and immune evasion: insights from Ebola virus and Marburg virus

I Messaoudi, GK Amarasinghe, CF Basler - Nature Reviews …, 2015 - nature.com
Ebola viruses and Marburg viruses, members of the filovirus family, are zoonotic pathogens
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …

Comparative transcriptomics in Ebola Makona-infected ferrets, nonhuman primates, and humans

RW Cross, E Speranza, V Borisevich… - The Journal of …, 2018 - academic.oup.com
The domestic ferret is a uniformly lethal model of infection for 3 species of Ebolavirus known
to be pathogenic in humans. Reagents to systematically analyze the ferret host response to …

[HTML][HTML] The role of cytokines and chemokines in filovirus infection

SL Bixler, AJ Goff - Viruses, 2015 - mdpi.com
Ebola-and marburgviruses are highly pathogenic filoviruses and causative agents of viral
hemorrhagic fever. Filovirus disease is characterized by a dysregulated immune response …

Innate immune responses of bat and human cells to filoviruses: commonalities and distinctions

IV Kuzmin, TM Schwarz, PA Ilinykh, I Jordan… - Journal of …, 2017 - Am Soc Microbiol
ABSTRACT Marburg (MARV) and Ebola (EBOV) viruses are zoonotic pathogens that cause
severe hemorrhagic fever in humans. The natural reservoir of MARV is the Egyptian rousette …

Comparative transcriptomics highlights the role of the activator protein 1 transcription factor in the host response to ebolavirus

JW Wynne, S Todd, V Boyd, M Tachedjian… - Journal of …, 2017 - Am Soc Microbiol
Ebolavirus and Marburgvirus comprise two genera of negative-sense single-stranded RNA
viruses that cause severe hemorrhagic fevers in humans. Despite considerable research …

[HTML][HTML] The glycoproteins of all filovirus species use the same host factors for entry into bat and human cells but entry efficiency is species dependent

M Hoffmann, M González Hernández, E Berger… - PLoS …, 2016 - journals.plos.org
Ebola and marburgviruses, members of the family Filoviridae, can cause severe
hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in …