Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model

Y Zhao, C Wang, B Qiu, C Li, H Wang, H Jin, W Gai… - Antiviral research, 2017 - Elsevier
Abstract Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection
caused by a coronavirus (CoV), MERS-CoV. With the continuing spread of MERS-CoV …

Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection

J Zhao, RAPM Perera, G Kayali, D Meyerholz… - Journal of …, 2015 - Am Soc Microbiol
Middle East respiratory syndrome (MERS) is a highly lethal pulmonary infection. Serum from
convalescent MERS patients may provide some benefit but is not readily available. In …

[HTML][HTML] Anti-S1 MERS-COV IgY specific antibodies decreases lung inflammation and viral antigen positive cells in the human transgenic mouse model

AT Abbas, SA El-Kafrawy, SS Sohrab, AA Tabll… - Vaccines, 2020 - mdpi.com
The Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in 2012 and
causes severe and often fatal acute respiratory illness in humans. No approved prophylactic …

Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus

Y Deng, J Lan, L Bao, B Huang, F Ye… - Emerging Microbes & …, 2018 - Taylor & Francis
The persistent public health threat of infection with Middle East respiratory syndrome
coronavirus (MERS-CoV) highlights the need for an effective and safe MERS-CoV vaccine …

[HTML][HTML] Immunotherapeutic efficacy of IgY antibodies targeting the full-length spike protein in an animal model of middle east respiratory syndrome coronavirus …

SA El-Kafrawy, AT Abbas, SS Sohrab, AA Tabll… - Pharmaceuticals, 2021 - mdpi.com
Identified in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) causes
severe and often fatal acute respiratory illness in humans. No approved prophylactic or …

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

D Corti, J Zhao, M Pedotti, L Simonelli… - Proceedings of the …, 2015 - National Acad Sciences
Middle East Respiratory Syndrome (MERS) is a highly lethal pulmonary infection caused by
a previously unidentified coronavirus (CoV), likely transmitted to humans by infected camels …

[HTML][HTML] Characterization of the immune response of MERS-CoV vaccine candidates derived from two different vectors in mice

E Li, F Yan, P Huang, H Chi, S Xu, G Li, C Liu, N Feng… - Viruses, 2020 - mdpi.com
Middle East respiratory syndrome (MERS) is an acute, high-mortality-rate, severe infectious
disease caused by an emerging MERS coronavirus (MERS-CoV) that causes severe …

[HTML][HTML] Inactivated rabies virus vectored MERS-coronavirus vaccine induces protective immunity in mice, camels, and alpacas

H Chi, Y Wang, E Li, X Wang, H Wang, H Jin… - Frontiers in …, 2022 - frontiersin.org
Middle East respiratory syndrome coronavirus (MERS-CoV) is an emergent coronavirus that
has caused frequent zoonotic events through camel-to-human spillover. An effective camelid …

Newcastle disease virus-based MERS-CoV candidate vaccine elicits high-level and lasting neutralizing antibodies in Bactrian camels

RQ Liu, JY Ge, JL Wang, S Yu, HL Zhang… - Journal of integrative …, 2017 - Elsevier
Middle East respiratory syndrome coronavirus (MERS-CoV), a member of the Coronaviridae
family, is the causative pathogen for MERS that is characterized by high fever, pneumonia …

Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets

N van Doremalen, D Falzarano, T Ying, E de Wit… - Antiviral research, 2017 - Elsevier
Abstract Cases of Middle East respiratory syndrome coronavirus (MERS-CoV) continue to
be identified and with a lack of effective clinical treatment and no preventative strategies …