Low intensity pulsed ultrasound enhanced mesenchymal stem cell recruitment through stromal derived factor-1 signaling in fracture healing

FY Wei, KS Leung, G Li, J Qin, SKH Chow, S Huang… - PloS one, 2014 - journals.plos.org
Low intensity pulsed ultrasound (LIPUS) has been proven effective in promoting fracture
healing but the underlying mechanisms are not fully depicted. We examined the effect of …

Applications of exogenous mesenchymal stem cells and low intensity pulsed ultrasound enhance fracture healing in rat model

WH Cheung, WC Chin, FY Wei, G Li… - Ultrasound in medicine & …, 2013 - Elsevier
The present study aimed to investigate the effects of combined treatment of exogenous
mesenchymal stem cells (MSCs) and low intensity pulsed ultrasound (LIPUS) on fracture …

Low‐intensity pulsed ultrasound accelerates fracture healing by stimulation of recruitment of both local and circulating osteogenic progenitors

K Kumagai, R Takeuchi, H Ishikawa… - Journal of …, 2012 - Wiley Online Library
We investigated the effect of low‐intensity pulsed ultrasound (LIPUS) on the homing of
circulating osteogenic progenitors to the fracture site. Parabiotic animals were formed by …

Low-intensity pulsed ultrasound (LIPUS) and cell-to-cell communication in bone marrow stromal cells

K Sena, SR Angle, A Kanaji, C Aher, DG Karwo… - Ultrasonics, 2011 - Elsevier
Low-intensity pulsed ultrasound (LIPUS) is an established therapy for fracture repair and
has been used widely in the clinics, but its underlying mechanism of action remains unclear …

Low-intensity pulsed ultrasound (LIPUS) inhibits LPS-induced inflammatory responses of osteoblasts through TLR4–MyD88 dissociation

J Nakao, Y Fujii, J Kusuyama, K Bandow, K Kakimoto… - Bone, 2014 - Elsevier
Previous reports have shown that osteoblasts are mechano-sensitive. Low-intensity pulsed
ultrasound (LIPUS) induces osteoblast differentiation and is an established therapy for bone …

Low‑intensity pulsed ultrasound promotes periodontal ligament stem cell migration through TWIST1‑mediated SDF‑1 expression Corrigendum in/10.3892/ijmm …

Y Wang, J Li, Y Qiu, B Hu, J Chen… - International …, 2018 - spandidos-publications.com
Low‑intensity pulsed ultrasound (LIPUS) is a non‑invasive therapeutic treatment for
accelerating fracture healing. A previous study from our group demonstrated that LIPUS has …

Low-intensity pulsed ultrasound regulates proliferation and differentiation of osteoblasts through osteocytes

L Li, Z Yang, H Zhang, W Chen, M Chen… - … and biophysical research …, 2012 - Elsevier
Low-intensity pulsed ultrasound (LIPUS) has been used as a safe and effective modality to
enhance fracture healing. As the most abundant cells in bone, osteocytes orchestrate …

Higher-intensity ultrasound accelerates fracture healing via mechanosensitive ion channel Piezo1

S Inoue, C Li, J Hatakeyama, H Jiang, H Kuroki… - Bone, 2023 - Elsevier
Osteoporosis-related fractures are a major public health problem. Mechanobiological
stimulation utilizing low-intensity pulsed ultrasound (LIPUS) is the most widely accepted …

Transforming growth factor-β1 mediates the effects of low-intensity pulsed ultrasound in chondrocytes

S Mukai, H Ito, Y Nakagawa, H Akiyama… - Ultrasound in medicine …, 2005 - Elsevier
Low-intensity pulsed ultrasound (LIPUS) has been shown to accelerate fracture healing, but
the precise mechanism is still unknown. We used aggregate chondrocyte culture system to …

Low-intensity pulsed ultrasound accelerated callus formation, angiogenesis and callus remodeling in osteoporotic fracture healing

WH Cheung, SK Chow, MH Sun, L Qin… - Ultrasound in medicine & …, 2011 - Elsevier
Osteoporotic fracture is a critical medico-social challenge leading to burdens in health care
costs and hospital bed stays. Low-intensity pulsed ultrasound (LIPUS) was reported to …