Zebrafish larvae as a behavioral model in neuropharmacology

RM Basnet, D Zizioli, S Taweedet, D Finazzi, M Memo - Biomedicines, 2019 - mdpi.com
Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark
conditions, following the development of a swim bladder at 4 days post fertilization. This …

[PDF][PDF] Zebrafish embryos and larvae in behavioural assays

F Ahmad, LPJJ Noldus, RAJ Tegelenbosch… - …, 2012 - researchgate.net
Zebrafish embryos and early larvae are becoming increasingly important as models in
biomedical research because of their low cost, high throughput and potential as a …

Behavioral screening for neuroactive drugs in zebrafish

J Rihel, AF Schier - Developmental neurobiology, 2012 - Wiley Online Library
The larval zebrafish has emerged as a vertebrate model system amenable to small molecule
screens for probing diverse biological pathways. Two large‐scale small molecule screens …

Zebrafish larvae behavior models as a tool for drug screenings and pre-clinical trials: a review

JGS Rosa, C Lima, M Lopes-Ferreira - International journal of molecular …, 2022 - mdpi.com
To discover new molecules or review the biological activity and toxicity of therapeutic
substances, drug development, and research relies on robust biological systems to obtain …

Quantification of locomotor activity in larval zebrafish: considerations for the design of high-throughput behavioral studies

JJ Ingebretson, MA Masino - Frontiers in neural circuits, 2013 - frontiersin.org
High-throughput behavioral studies using larval zebrafish often assess locomotor activity to
determine the effects of experimental perturbations. However, the results reported by …

Automated analysis of behavior in zebrafish larvae

R Creton - Behavioural brain research, 2009 - Elsevier
Zebrafish larvae have become a popular model system to examine genetic and
environmental factors that affect behavior. However, studying complex behavior in large …

Locomotion in larval zebrafish: Influence of time of day, lighting and ethanol

RC MacPhail, J Brooks, DL Hunter, B Padnos, TD Irons… - Neurotoxicology, 2009 - Elsevier
The increasing use of zebrafish (Danio rerio) in developmental research highlights the need
for a detailed understanding of their behavior. We studied the locomotion of individual …

Statistical analysis of zebrafish locomotor response

Y Liu, R Carmer, G Zhang, P Venkatraman, SA Brown… - PloS one, 2015 - journals.plos.org
Zebrafish larvae display rich locomotor behaviour upon external stimulation. The movement
can be simultaneously tracked from many larvae arranged in multi-well plates. The resulting …

Locomotor repertoire of the larval zebrafish: swimming, turning and prey capture

SA Budick, DM O'Malley - Journal of Experimental Biology, 2000 - journals.biologists.com
Larval zebrafish (Brachydanio rerio) are a popular model system because of their genetic
attributes, transparency and relative simplicity. They have approximately 200 neurons that …

A novel high-throughput imaging system for automated analyses of avoidance behavior in zebrafish larvae

SD Pelkowski, M Kapoor, HA Richendrfer… - Behavioural brain …, 2011 - Elsevier
Early brain development can be influenced by numerous genetic and environmental factors,
with long-lasting effects on brain function and behavior. The identification of these factors is …