Mannose-rich oligosaccharides-functionalized selenium nanoparticles mediates macrophage reprogramming and inflammation resolution in ulcerative colitis

H Yang, C Zhu, W Yuan, X Wei, C Liu, J Huang… - Chemical Engineering …, 2022 - Elsevier
Inflammatory bowel disease (IBD) is a global disease and usually classified into Crohn's
disease (CD) and ulcerative colitis (UC), in which the inflammatory response is known to …

Selenium nanoparticles decorated with Ulva lactuca polysaccharide potentially attenuate colitis by inhibiting NF-κB mediated hyper inflammation

C Zhu, S Zhang, C Song, Y Zhang, Q Ling… - Journal of …, 2017 - Springer
Abstract Background Selenium (Se) is an essential micronutrient trace element and an
established nutritional antioxidant. Low Se status exacerbates inflammatory bowel diseases …

Eucommia ulmoides polysaccharide modified nano-selenium effectively alleviated DSS-induced colitis through enhancing intestinal mucosal barrier function and …

R Ye, Q Guo, J Huang, Z Wang, Y Chen… - Journal of …, 2023 - Springer
Ulcerative colitis (UC) is currently the most common inflammatory bowel disease (IBD). Due
to its diverse and complex causes, there is no cure at present, and researchers are …

Synthesis, characterization of low molecular weight chitosan selenium nanoparticles and its effect on dss-induced ulcerative colitis in mice

SJ Peng, DT Ye, J Zheng, YR Xue, L Lin… - International Journal of …, 2022 - mdpi.com
Selenium nanoparticles have attracted extensive attention due to their good bioavailability
and activity. In the present study, a new form of selenium nanoparticle (Low molecular …

An oral nano-antioxidant for targeted treatment of inflammatory bowel disease by regulating macrophage polarization and inhibiting ferroptosis of intestinal cells

J Yang, Y Bai, S Shen, X Tao, C Ma, B Fu, Q Dai… - Chemical Engineering …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a chronic inflammatory disease that characterized by
excessive reactive oxygen species (ROS) and high ferroptosis. The ROS plays an essential …

Biogenic nanoselenium particles effectively attenuate oxidative stress-induced intestinal epithelial barrier injury by activating the Nrf2 antioxidant pathway

D Song, Y Cheng, X Li, F Wang, Z Lu… - … Applied Materials & …, 2017 - ACS Publications
In the present study, a new form of selenium nanoparticle (biogenic nanoselenium (BNS)
particles) was synthesized using bacteria. The protection of BNS particles against oxidative …

Biosynthesis of Polysaccharides-Capped Selenium Nanoparticles Using Lactococcus lactis NZ9000 and Their Antioxidant and Anti-inflammatory Activities

C Xu, L Qiao, L Ma, S Yan, Y Guo, X Dou… - Frontiers in …, 2019 - frontiersin.org
Lactococcus lactis (L. lactis) NZ9000, which has been genetically modified, is the most
commonly used host strain for nisin regulated gene expression. Selenium (Se) is an …

Porous selenium nanozymes targeted scavenging ROS synchronize therapy local inflammation and sepsis injury

X Chen, X Zhu, Y Gong, G Yuan, J Cen, Q Lie… - Applied Materials …, 2021 - Elsevier
Excessive reactive oxygen species (ROS) is the main factor leading to high mortality in local
inflammation and sepsis. Therefore, developing efficient ROS scavenger in pro-inflammatory …

Multi-strain-probiotic-loaded nanoparticles reduced Colon inflammation and orchestrated the expressions of tight junction, NLRP3 Inflammasome and Caspase-1 …

AG Alkushi, ST Elazab, A Abdelfattah-Hassan… - Pharmaceutics, 2022 - mdpi.com
Gut modulation by multi-strain probiotics (MSPs) is considered an effective strategy for
treating inflammatory bowel disease (IBD). The combination of nanomaterial-based MSPs …

Biogenic selenium nanoparticles synthesized by Lactobacillus casei ATCC 393 alleviate intestinal epithelial barrier dysfunction caused by oxidative stress via Nrf2 …

C Xu, L Qiao, L Ma, Y Guo, X Dou, S Yan… - International journal …, 2019 - Taylor & Francis
Background: Selenium (Se) can exert antioxidative activity and prevent the body from
experiencing oxidative injury. Biogenic Se nanoparticles (SeNPs) synthesized by probiotics …