Characterization of pharmaceutical tablets using UV hyperspectral imaging as a rapid in-line analysis tool

M Al Ktash, M Stefanakis, B Boldrini, E Ostertag… - Sensors, 2021 - mdpi.com
A laboratory prototype for hyperspectral imaging in ultra-violet (UV) region from 225 to 400
nm was developed and used to rapidly characterize active pharmaceutical ingredients (API) …

Hyperspectral imaging technology for pharmaceutical analysis

SJ Hamilton, RA Lodder - … Nanotechnology Architectures and …, 2002 - spiedigitallibrary.org
The sensitivity and spatial resolution of hyperspectral imaging instruments are tested in this
paper using pharmaceutical applications. The first experiment tested the hypothesis that a …

Real-time determination and visualization of two independent quantities during a manufacturing process of pharmaceutical tablets by near-infrared hyperspectral …

T Nishii, K Matsuzaki, S Morita - International Journal of Pharmaceutics, 2020 - Elsevier
During pharmaceutical manufacturing, line-scan hyperspectral imaging enables us to collect
several electromagnetic spectra at each pixel in a two-dimensional plane for each tablet …

Hyperspectral imaging as a part of pharmaceutical product design

J Bøtker, JX Wu, J Rantanen - Data Handling in Science and Technology, 2019 - Elsevier
Imaging is getting an important element of the modern drug development process. Different
hyperspectral imaging tools can provide in-depth understanding of complex pharmaceutical …

Content uniformity of pharmaceutical solid dosage forms by near infrared hyperspectral imaging: a feasibility study

C Gendrin, Y Roggo, C Collet - Talanta, 2007 - Elsevier
Near-infrared imaging systems simultaneously record spectral and spatial information. Each
measurement generates a data cube containing several thousand spectra. Chemometric …

Practical issues of hyperspectral imaging analysis of solid dosage forms

JM Amigo - Analytical and bioanalytical chemistry, 2010 - Springer
Hyperspectral imaging techniques have widely demonstrated their usefulness in different
areas of interest in pharmaceutical research during the last decade. In particular, middle …

Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging

F Franch-Lage, JM Amigo, E Skibsted… - International journal of …, 2011 - Elsevier
The inclusion of hyperspectral imaging systems in the manufacturing and development of
pharmaceutical products is allowing a successful improvement in the quality control of solid …

Infrared hyperspectral imaging for qualitative analysis of pharmaceutical solid forms

Y Roggo, A Edmond, P Chalus, M Ulmschneider - Analytica Chimica Acta, 2005 - Elsevier
A multi-spectral imaging spectrometer records simultaneously spectra and spatial
information of samples. The infrared (IR) imaging system used was the Hyperion 3000 …

Hyperspectral techniques in analysis of oral dosage forms

SJ Hamilton, AE Lowell… - Journal of Biomedical …, 2002 - spiedigitallibrary.org
Pharmaceutical oral dosage forms are used in this paper to test the sensitivity and spatial
resolution of hyperspectral imaging instruments. The first experiment tested the hypothesis …

In-process control assay of pharmaceutical microtablets using hyperspectral imaging coupled with multivariate analysis

LM Kandpal, J Tewari, N Gopinathan, P Boulas… - Analytical …, 2016 - ACS Publications
Monitoring the amount of active pharmaceutical ingredient (API) in finished dosage form is
important to ensure the content uniformity of the product. In this report, we summarize the …