Skeletal muscle is a highly plastic tissue that remarkably adapts to diverse stimuli including
exercise, injury, disuse, and, as discussed here, aging. Humans achieve peak skeletal …

Highlights•Age-related loss of muscle mass and function is a major contributor to
frailty.•Muscles show loss of fibres, atrophy, poor regeneration and adaptive responses.• …

Aging is associated with a progressive decline of muscle mass, strength, and quality, a
condition described as sarcopenia of aging. Despite the significance of skeletal muscle …

A substantial loss of muscle mass and strength (sarcopenia), a decreased regenerative
capacity, and a compromised physical performance are hallmarks of aging skeletal muscle …

The world population is ageing rapidly. As society ages, the incidence of physical limitations
is dramatically increasing, which reduces the quality of life and increases healthcare …

Sarcopenia, an age-related condition characterized by progressive skeletal muscle
degeneration, might exist as one of the primary clinical conditions underlying severe …

Situations such as the recovery from injury and illness can lead to enforced periods of
muscle disuse or unloading. Such circumstances lead to rapid skeletal muscle atrophy, loss …

Sarcopenia is a debilitating skeletal muscle disease that accelerates in the last decades of
life and is characterized by marked deficits in muscle strength, mass, quality, and metabolic …

Some of the most serious consequences of ageing are its effects on skeletal muscle. The
term 'sarcopenia'describes the slow but progressive loss of muscle mass with advancing …

As we age, there is an age-related loss in skeletal muscle mass and strength, known as
sarcopenia. Sarcopenia results in a decrease in mobility and independence, as well as an …