Progressive multiple sclerosis (MS) is characterized by unrelenting neurodegeneration,
which causes cumulative disability and is refractory to current treatments. Drug development …

Despite recent advances in the diagnosis and treatment of multiple sclerosis, we still lack a
consensus regarding the causes, pathogenesis, and mechanisms of disease progression …

Multiple sclerosis (MS) is a neurological disease characterized by multifocal lesions and
smoldering pathology. Although single-cell analyses provided insights into cytopathology …

In recent years it has become clear that the neuronal compartment already plays an
important role early in the pathology of multiple sclerosis (MS). Neuronal injury in the course …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that
involves demyelination and axonal degeneration. Although substantial progress has been …

Multiple sclerosis (MS) is a neuroinflammatory disease with a relapsing–remitting disease
course at early stages, distinct lesion characteristics in cortical grey versus subcortical white …

Multiple sclerosis (MS) is the most frequent chronic inflammatory disease of the CNS, and
imposes major burdens on young lives. Great progress has been made in understanding …

Classical biological methods involving analyses of one or several genes have been the
mainstay for studying the pathogenesis of neurodegenerative disorders. However, it has …

Multiple sclerosis (MS) is a multifocal and progressive inflammatory disease of the central
nervous system (CNS). However, the compartmentalized pathology of the disease affecting …

Multiple sclerosis (MS) is an inflammatory, autoimmune, demyelinating disease of the
central nervous system (CNS) that usually starts as a relapsing-remitting disease. In most …