Oral delivery of biopharmaceutics drug disposition classification system (BDDCS) Class II or
IV drugs with poor aqueous solubility and poor enzymatic and/or metabolic stability is very …

Context: Approximately 400 million persons worldwide have chronic hepatitis B. This is due
to problems associated with vaccine delivery, stability and cost. Hence the present …

Nowadays, the use of statistical approaches, ie, Box–Bhenken designs, are becoming very
effective for developing and optimizing pharmaceutical drug formulations. In the current …

Hepatitis B virus (HBV) capsid assembly modulators (CAMs) represent a promising
therapeutic approach for the treatment of HBV infection. In this study, the hit compound CDI …

Purpose: Biopharmaceutics classification system (BCS) class IV compounds, exhibits least
oral bioavailability, low solubility and intestinal permeability among all pharmaceutical …

Background The overall objective was to prepare a highly accurate nanocarrier system of
mesalamine for the treatment of ulcerative colitis with increased therapeutic efficacy and …

The study was designed to prepare and evaluate albumin nanoparticles containing antiviral
drug abacavir sulphate. Various batches of albumin nanoparticles containing abacavir …

The hepatitis B virus (HBV) capsid assembly modulators (CAMs) have been developed as
effective anti-HBV agents in the treatment of chronic HBV infection by targeting the HBV core …

The design of effective vaccine delivery system is opening up new feasibilities for making
immunization more safe and efficient. In this study, recombinant hepatitis B virus surface …

Bioadhesion can be described as an interfacial phenomenon between the biological
membrane and substrate, held together by interfacial forces for an extended period of time …