Not only redox: the multifaceted activity of cerium oxide nanoparticles in cancer prevention and therapy

F Corsi, F Caputo, E Traversa, L Ghibelli - Frontiers in oncology, 2018 - frontiersin.org
Much information is accumulating on the effect of cerium oxide nanoparticles (CNPs) as cell-
protective agents, reducing oxidative stress through their unique ability of scavenging …

Cerium oxide nanoparticles in cancer

Y Gao, K Chen, J Ma, F Gao - OncoTargets and therapy, 2014 - Taylor & Francis
With the development of many nanomedicines designed for tumor therapy, the diverse
abilities of cerium oxide nanoparticles (CONPs) have encouraged researchers to pursue …

Anticancer therapeutic effect of cerium-based nanoparticles: Known and unknown molecular mechanisms

MJN Amaldoss, R Mehmood, JL Yang, P Koshy… - Biomaterials …, 2022 - pubs.rsc.org
Cerium-based nanoparticles (CeNPs), particularly cerium oxide (CeO2), have been studied
extensively for their antioxidant and prooxidant properties. However, their complete redox …

[HTML][HTML] Cerium oxide nanoparticles: potential applications for cancer and other diseases

MS Wason, J Zhao - American journal of translational research, 2013 - ncbi.nlm.nih.gov
The diverse abilities of cerium oxide nanoparticles (CONPs) have encouraged researchers
to pursue CONPs as a therapeutic agent to treat a number of diseases, including cancer. In …

Pro-oxidant therapeutic activities of cerium oxide nanoparticles in colorectal carcinoma cells

A Datta, S Mishra, K Manna, KD Saha, S Mukherjee… - ACS …, 2020 - ACS Publications
Given that basal levels of reactive oxygen species (ROS) are higher in cancer cells, there is
a growing school of thought that endorses pro-oxidants as potential chemotherapeutic …

Cerium oxide nanoparticles re-establish cell integrity checkpoints and apoptosis competence in irradiated HaCat cells via novel redox-independent activity

F Caputo, A Giovanetti, F Corsi, V Maresca… - Frontiers in …, 2018 - frontiersin.org
Cerium oxide nanoparticles (CNPs) are potent radical scavengers protecting cells from
oxidative insults, including ionizing radiation. Here we show that CNPs prevent X-ray …

Combination of conventional chemotherapeutics with redox-active cerium oxide nanoparticles—a novel aspect in cancer therapy

M Sack, L Alili, E Karaman, S Das, A Gupta… - Molecular cancer …, 2014 - AACR
Nanotechnology is becoming an important field of biomedical and clinical research and the
application of nanoparticles in disease may offer promising advances in treatment of many …

[HTML][HTML] Redox-active cerium oxide nanoparticles protect human dermal fibroblasts from PQ-induced damage

C von Montfort, L Alili, S Teuber-Hanselmann… - Redox biology, 2015 - Elsevier
Recently, it has been published that cerium (Ce) oxide nanoparticles (CNP; nanoceria) are
able to downregulate tumor invasion in cancer cell lines. Redox-active CNP exhibit both …

Cerium oxide nanoparticles and their importance in cell signaling pathways for predicting cellular behavior

A Pesaraklou, MM Matin - Nanomedicine, 2020 - Taylor & Francis
Cerium oxide nanoparticles (CeO2-NPs) have prolifically attracted immense interest of
researchers due to their prominent anti-oxidant nature. However, these characteristics are …

Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity

M Pešić, A Podolski-Renić, S Stojković… - Chemico-biological …, 2015 - Elsevier
Data on medical applications of cerium oxide nanoparticles CeO 2 (CONP) are promising,
yet information regarding their action in cells is incomplete and there are conflicting reports …