Haemostasis and thrombosis are complex, multifactorial processes. There is an evolving
understanding of the mechanisms influencing vascular occlusion and the role of …

The crucial role of platelets in primary hemostasis and repair of injured endothelium is well
established, as is their role in atherothrombosis. No other single cell type is responsible for …

Platelets are important actors of cardiovascular diseases (CVD). Current antiplatelet drugs
that inhibit platelet aggregation have been shown to be effective in CVD treatment. However …

Cardiovascular disease remains the main cause of death worldwide. For this reason,
strategies for the primary prevention of atherosclerosis and atherosclerosis-related …

Platelets—blood cells continuously produced from megakaryocytes mainly in the bone
marrow—are implicated not only in haemostasis and arterial thrombosis, but also in other …

The central importance of platelets in the development of arterial thrombosis and
cardiovascular disease is well established. No other single cell type is responsible for as …

Abstract Essentials• A State of the Art lecture “Clotting factors and atherothrombosis” was
presented at the ISTH congress 2017.• Coagulation proteins are not only involved in …

Haemostasis stops bleeding at the site of vascular injury and maintains the integrity of blood
vessels through clot formation. This regulated physiological process consists of complex …

The platelet, once thought to be solely involved in clot formation, is now known to be a key
mediator in various others processes such as inflammation, thrombosis, and atherosclerosis …

Platelets are small anucleate cells generated from megakaryocytes in the bone marrow.
After being released into the circulation, platelets play key roles in the surveillance of …