The complete set of viable deletion strains in Saccharomyces cerevisiae was screened for
sensitivity of mutants to five oxidants to identify cell functions involved in resistance to …

Genome-wide analyses of yeast provide insight into cellular responses to reactive oxygen
species (ROS). Many deletion mutants are sensitive to at least one ROS, but no one oxidant …

Although oxidative stress is involved in many human diseases, little is known of its molecular
basis in eukaryotes. In a genetic approach, S. cerevisiae was used to identify elements …

The yeast Saccharomyces cerevisiae has been extensively utilised to address the
mechanisms underlying the oxidative stress response. The antioxidant defences can be …

▪ Abstract The glutathione-and thioredoxin-dependent reduction systems are responsible for
maintaining the reduced environment of the Escherichia coli and Saccharomyces cerevisiae …

There is rapidly expanding interest into the protective systems against reactive oxygen
species (ROS) in the eukaryotic cell, now that the links between oxidative damage, various …

All aerobically growing organisms suffer exposure to oxidative stress, caused by partially
reduced forms of molecular oxygen, known as reactive oxygen species (ROS). These are …

Prolonged exposure to hyperoxia represents a serious danger to cells, yet little is known
about the specific cellular factors that affect hyperoxia stress. By screening the yeast deletion …

Proliferating mammalian cells exhibit a broad spectrum of responses to oxidative stress,
depending on the stress level encountered. Very low levels of hydrogen peroxide, eg, 3 to …

Background Living cells constantly sense and adapt to redox shifts by the induction of genes
whose products act to maintain the cellular redox environment. In the eukaryote …