Natural withanolides: an overview

LX Chen, H He, F Qiu - Natural product reports, 2011 - pubs.rsc.org
Covering: August 1996 to March 2010 Withanolides are a group of naturally occurring C28
steroids built on an ergostane skeleton functionalized at carbons 1, 22 and 26, commonly …

Natural withanolides, an update

G Xia, S Cao, L Chen, F Qiu - Natural Product Reports, 2022 - pubs.rsc.org
Covering: March 2010 to December 2020. Previous review: Nat. Prod. Rep., 2011, 28, 705
This review summarizes the latest progress and perspectives on the structural classification …

Withanolides from the genus Physalis: a review on their phytochemical and pharmacological aspects

M Huang, JX He, HX Hu, K Zhang… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives Withanolides are a group of modified C28 ergostane-type steroids with a C-22, C-
26 δ-lactone side chain or a C-23, C-26 γ-lactone side chain. They enjoy a limited …

Withanolides and related ergostane-type steroids

E Glotter - Natural product reports, 1991 - pubs.rsc.org
Withanolides and Related Ergostane-type Steroids A Page 1 Withanolides and Related
Ergostane-type Steroids E. Glotter Faculty of Agriculture, The Hebrew University of …

Withanolides and related steroids

RI Misico, VE Nicotra, JC Oberti, G Barboza… - Progress in the …, 2011 - Springer
Since the isolation of the first withanolides in the mid-1960s, over 600 new members of this
group of compounds have been described, with most from genera of the plant family …

Withanolide A is inherently de novo biosynthesized in roots of the medicinal plant Ashwagandha (Withania somnifera)

RS Sangwan, ND Chaurasiya, P Lal… - Physiologia …, 2008 - Wiley Online Library
Ashwagandha (Withania somnifera Dunal., Solanaceae) is one of the most reputed
medicinal plants of Ayurveda, the traditional medical system. Several of its traditionally …

Withasteroids, a growing group of naturally occurring steroidal lactones

J Cárdenas, B Esquivel, M Gupta, AB Ray… - Fortschritte der Chemie …, 1994 - Springer
Withasteroids are a group of naturally occurring C 28-steroidal lactones built on an intact or
rearranged ergostane framework. Withaferin A (64), the first member of this group of …

Antiproliferative withanolides from the Solanaceae: A structure–activity study

H Zhang, AK Samadi, MS Cohen… - Pure and Applied …, 2012 - degruyter.com
As part of our search for bioactive compounds from plant biodiversity, 29 withanolides were
recently isolated from three members of the Solanaceae: Physalis longifolia, Vassobia …

Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

MH Mirjalili, E Moyano, M Bonfill, RM Cusido… - Molecules, 2009 - mdpi.com
Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that
has been used in Ayurvedic and indigenous medicine for over 3,000 years. In view of its …

Biological activity of withanolides

RD Budhiraja, P Krishan, S Sudhir - 2000 - nopr.niscpr.res.in
A large number of withanolides are isolated from solanaceous plants and some derivatives
are also prepared. Some of the withanolides, mainly Withaferin A (WA), Withanolide D (WD) …