The anti-inflammatory effects of testosterone

VE Bianchi - Journal of the endocrine society, 2019 - academic.oup.com
Low plasma testosterone (T) levels correlated with metabolic syndrome, cardiovascular
diseases, and increased mortality risk. T exerts a significant effect on the regulation of …

[HTML][HTML] The relationship between circulating testosterone and inflammatory cytokines in men

NV Mohamad, SK Wong, WNW Hasan, JJ Jolly… - The Aging …, 2019 - Taylor & Francis
Testosterone is the predominant gonadal androgen in men. Low testosterone levels are
found to be associated with an increased in metabolic risk and systematic inflammation …

The effect of testosterone replacement therapy on adipocytokines and C-reactive protein in hypogonadal men with type 2 diabetes

D Kapoor, S Clarke, R Stanworth… - European journal of …, 2007 - academic.oup.com
Objective Serum testosterone levels are known to inversely correlate with insulin sensitivity
and obesity in men. Furthermore, there is evidence to suggest that testosterone replacement …

The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men

CJ Malkin, PJ Pugh, RD Jones, D Kapoor… - The Journal of …, 2004 - academic.oup.com
Testosterone has immune-modulating properties, and current in vitro evidence suggests that
testosterone may suppress the expression of the proinflammatory cytokines TNFα, IL-1β …

Do androgens modulate the pathophysiological pathways of inflammation? Appraising the contemporary evidence

A Traish, J Bolanos, S Nair, F Saad… - Journal of clinical …, 2018 - mdpi.com
The role of testosterone in the pathophysiology of inflammation is of critical clinical
importance; however, no universal mechanism (s) has been advanced to explain the …

Randomized controlled trials–mechanistic studies of testosterone and the cardiovascular system

TH Jones, DM Kelly - Asian journal of andrology, 2018 - journals.lww.com
Testosterone deficiency is common in men with cardiovascular disease (CVD), and
randomized placebo-controlled trials (RCTs) have reported beneficial effects of testosterone …

Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double …

SY Kalinchenko, YA Tishova… - Clinical …, 2010 - Wiley Online Library
Objective Men with the metabolic syndrome (MetS) have low plasma testosterone (T) levels.
The aim of this study was to establish whether the normalization of plasma T improves the …

Associations between visceral adipose tissue, inflammation and sex steroid concentrations in men

A Gautier, F Bonnet, S Dubois, C Massart… - Clinical …, 2013 - Wiley Online Library
Context In men, obesity and the metabolic syndrome are accompanied by decreased
testosterone levels, but little is known about the associations between visceral adipose …

Impact of testosterone on body fat composition

C De Maddalena, S Vodo, A Petroni… - Journal of cellular …, 2012 - Wiley Online Library
An excessive food supply has resulted in an increasing prevalence of overweight and
obesity, conditions accompanied by serious health problems. Several studies have …

Negative association between testosterone concentration and inflammatory markers in young men: a nested cross-sectional study

J Bobjer, M Katrinaki, C Tsatsanis… - PloS one, 2013 - journals.plos.org
Objective Low grade systemic inflammation (LGSI) as well as androgen deficiency has in
older men been associated with several pathologies, including cardiovascular disease …