Monitoring dynamic changes in tumor immune markers are essential for predicting the
therapeutic responses of tumors to immunotherapy, as well as other traditional therapies …

CD44 receptor protein is found to be overexpressed by many tumors and is identified as one
of the most common cancer stem cell surface markers including tumors affecting colon …

Cytotoxic T cells initiate antitumor effects mainly through direct interactions with tumor cells.
As a counter to this, tumor cells can put the brakes on such T-cell activity via specific linkage …

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with no current effective
therapeutics. One of the main reasons for the low efficacy of PDAC immunotherapy is the …

A new combination strategy of an active loading and active targeting approach was applied
in this work. The liposomes actively loaded with Curcumin (CRM)(LipCRM) were decorated …

Immune checkpoint blockade (ICB) is an important strategy for cancer treatment and has
achieved remarkable clinical results. Further enhancement of the efficacy of ICB therapy with …

The PD-1/PD-L1 pathway blockade can generate a good clinical response by reducing
immunosuppression and provoking durable antitumor immunity. In addition to antibodies …

The specific binding ability of DNA–lipid micelles (DLMs) can be increased by the
introduction of an aptamer. However, supramolecular micellar structures based on self …

In this study, we developed a drug-loading liposome linked with two types of DNA aptamers
targeting the surface marker transmembrane glycoprotein mucin 1 antigen (MUC1) on …

Liposomes are among the most well-documented drug delivery systems in anticancer
therapy owing to their passive targeting capacities besides inherent biocompatibility and …