Although great advances in elucidating the molecular basis and pathogenesis of
Alzheimer's disease (AD) have been made and multifarious novel therapeutic approaches …

The goal of this review is to discuss how behavioral tests in mice relate to the pathological
and neuropsychological features seen in human Alzheimer's disease (AD), and present a …

Animal models are indispensable tools for Alzheimer disease (AD) research. Over the
course of more than two decades, an increasing number of complementary rodent models …

Alzheimer's disease (AD) is the most common origin of dementia in the elderly. Although the
cause of AD remains unknown, several factors have been identified that appear to play a …

Alzheimer's disease (AD), an irreversible neurodegenerative disease that progressively
impairs memory and cognitive judgment, severely affects the quality of life and imposes a …

Most mouse models for preclinical research into Alzheimer's disease (AD) rely on the
overexpression paradigm, in which familial AD (FAD)-related genes linked to amyloid …

Alzheimer's disease (AD) is one of the looming health crises of the near future. Increasing
lifespans and better medical treatment for other conditions mean that the prevalence of this …

Alzheimer's disease (AD) is a neurodegenerative disorder that nowadays affects more than
40 million people worldwide and it is predicted to exponentially increase in the coming …

Alzheimer disease (AD) is a medically and financially overwhelming condition, and
incidence rates are expected to triple by 2050. Despite decades of research in animal …

In Alzheimer's disease (AD), characteristic lesions develop in brain regions that subserve
cognitive functions, ultimately leading to dementia. There are now several lesioned or …