The burden of reliability: How measurement noise limits brain-behaviour predictions

M Gell, SB Eickhoff, A Omidvarnia, V Küppers, KR Patil… - BioRxiv, 2023 - biorxiv.org
Current major efforts in human neuroimaging research aim to understand individual
differences and identify biomarkers for clinical applications. One particularly promising …

Suboptimal phenotypic reliability impedes reproducible human neuroscience

A Nikolaidis, AA Chen, X He, R Shinohara… - BioRxiv, 2022 - biorxiv.org
Paragraph Biomarkers of behavior and psychiatric illness for cognitive and clinical
neuroscience remain out of reach–. Suboptimal reliability of biological measurements, such …

Harnessing reliability for neuroscience research

XN Zuo, T Xu, MP Milham - Nature human behaviour, 2019 - nature.com
Neuroscientists are amassing the large-scale datasets needed to study individual
differences and identify biomarkers. However, measurement reliability within individual …

[HTML][HTML] Beyond fingerprinting: Choosing predictive connectomes over reliable connectomes

ES Finn, MD Rosenberg - NeuroImage, 2021 - Elsevier
Recent years have seen a surge of research on variability in functional brain connectivity
within and between individuals, with encouraging progress toward understanding the …

[HTML][HTML] How to enhance the power to detect brain–behavior correlations with limited resources

B de Haas - Frontiers in human neuroscience, 2018 - frontiersin.org
Neuroscience has been diagnosed with a pervasive lack of statistical power and, in turn,
reliability. One remedy proposed is a massive increase of typical sample sizes. Parts of the …

Individual differences in cognitive performance are better predicted by global rather than localized BOLD activity patterns across the cortex

W Zhao, CE Palmer, WK Thompson, B Chaarani… - Cerebral …, 2021 - academic.oup.com
Despite its central role in revealing the neurobiological mechanisms of behavior,
neuroimaging research faces the challenge of producing reliable biomarkers for cognitive …

Interpreting Brain Biomarkers: Challenges and solutions in interpreting machine learning-based predictive neuroimaging

R Jiang, CW Woo, S Qi, J Wu… - IEEE signal processing …, 2022 - ieeexplore.ieee.org
Predictive modeling of neuroimaging data (predictive neuroimaging) for evaluating
individual differences in various behavioral phenotypes and clinical outcomes is of growing …

[HTML][HTML] Population heterogeneity in clinical cohorts affects the predictive accuracy of brain imaging

O Benkarim, C Paquola, B Park, V Kebets, SJ Hong… - PLoS …, 2022 - journals.plos.org
Brain imaging research enjoys increasing adoption of supervised machine learning for
single-participant disease classification. Yet, the success of these algorithms likely depends …

The challenges and prospects of brain-based prediction of behaviour

J Wu, J Li, SB Eickhoff, D Scheinost… - Nature human …, 2023 - nature.com
Relating individual brain patterns to behaviour is fundamental in system neuroscience.
Recently, the predictive modelling approach has become increasingly popular, largely due …

[PDF][PDF] Putting behaviour back into brain–behaviour correlation analyses

J Tiego, A Fornito - Aperture Neuro, 2022 - apertureneuro.org
A fundamental challenge for human neuroscience is to relate imprecise measures of the
brain with imprecise measures of behaviour. The recent study by Marek et al.(1) has …