Efficacy and outcome of remdesivir and tocilizumab combination against dexamethasone for the treatment of severe COVID-19: A randomized controlled trial

ATM Mohiuddin Chowdhury, A Kamal… - Frontiers in …, 2022 - frontiersin.org
Objective: In this study, we investigated the efficacy and safety of remdesivir and tocilizumab
combination therapy against dexamethasone for the management of severe COVID-19 …

Survival benefit of remdesivir in hospitalized COVID-19 patients with high SARS-CoV-2 viral loads and low-grade systemic inflammation

S Padilla, K Polotskaya, M Fernández… - Journal of …, 2022 - academic.oup.com
Objectives To assess the benefits of remdesivir in hospitalized COVID-19 patients receiving
combined immunomodulatory therapy (CIT) with dexamethasone and tocilizumab. Methods …

Prognostic factors for poor outcomes in patients with severe COVID-19 treated with remdesivir plus dexamethasone in Taiwan

YH Lai, YC Lee, IR Chen, SN Lin, YL Chang… - Journal of Microbiology …, 2023 - Elsevier
Abstract Background Coronavirus disease-2019 (COVID-19) remains a global public health
concern, and remdesivir plus dexamethasone combination therapy is suggested for patients …

Therapeutic efficacy and outcomes of remdesivir versus remdesivir with tocilizumab in severe SARS-CoV-2 infection

DM Vulturar, MA Neag, ȘC Vesa, AD Maierean… - International Journal of …, 2022 - mdpi.com
The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
generated many challenges to find an effective drug combination for hospitalized patients …

Efficacy of pharmacological interventions in COVID‐19: a network meta‐analysis

S Selvarajan, A Anandaradje… - British Journal of …, 2022 - Wiley Online Library
Aims To perform network meta‐analysis for a head‐to‐head comparison of various
interventions used in coronavirus disease 2019 (COVID‐19) on mortality, clinical recovery …

Effectiveness of remdesivir with and without dexamethasone in hospitalized patients with COVID-19

BT Garibaldi, K Wang, ML Robinson, SL Zeger… - medRxiv, 2020 - medrxiv.org
Rationale Remdesivir and dexamethasone reduced the severity of COVID-19 in clinical
trials. However, their individual or combined effectiveness in clinical practice remains …

Improved survival among hospitalized patients with coronavirus disease 2019 (COVID-19) treated with remdesivir and dexamethasone. A nationwide population …

T Benfield, J Bodilsen, C Brieghel… - Clinical Infectious …, 2021 - academic.oup.com
Background There are limited data on outcomes of moderate to severe coronavirus disease
2019 (COVID-19) among patients treated with remdesivir and dexamethasone in a real …

Remdesivir plus Dexamethasone in COVID-19: A cohort study of severe patients requiring high flow oxygen therapy or non-invasive ventilation

G De Pascale, SL Cutuli, S Carelli, R Xhemalaj… - PLoS …, 2022 - journals.plos.org
Introduction Remdesivir and Dexamethasone represent the cornerstone of therapy for
critically ill patients with acute hypoxemic respiratory failure caused by Coronavirus Disease …

Remdesivir Plus Dexamethasone Versus Dexamethasone Alone for the Treatment of Coronavirus Disease 2019 (COVID-19) Patients Requiring Supplemental O2 …

A Marrone, R Nevola, A Sellitto… - Clinical Infectious …, 2022 - academic.oup.com
Background Remdesivir is an antiviral used to treat coronavirus disease 2019 (COVID-19),
which improves some clinical outcomes. Dexamethasone has been shown to be effective in …

Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial

IO Rosas, G Diaz, RL Gottlieb, SM Lobo… - Intensive care …, 2021 - Springer
Purpose Trials of tocilizumab in patients with severe COVID-19 pneumonia have
demonstrated mixed results, and the role of tocilizumab in combination with other treatments …