Hepatitis is an inflammatory liver disease primarily caused by hepatitis A (HAV), B (HBV), C
(HCV), D (HDV), and E (HEV) viruses. The chronic forms of hepatitis resulting from HBV and …

Hepatitis C is an inflammatory liver disease caused by the single-stranded RNA (ssRNA)
hepatitis C virus (HCV). The genetic diversity of the virus and quasispecies produced during …

More than 240 million people around the world are chronically infected with hepatitis B virus
(HBV). Nucleos (t) ide analogs and interferon are the only two families of drugs to treat HBV …

After almost a decade of using CRISPR/Cas9 systems to edit target genes, CRISPR/Cas9
and related technologies are rapidly moving to clinical trials. Hepatitis B virus (HBV), which …

From its unexpected discovery as a bacterial adaptive immune system to its countless
applications as one of the most versatile gene-editing tools, the CRISPR/Cas9 system has …

Chronic hepatitis B (CHB) is caused by hepatitis B virus (HBV) infection. This disease is a
key issue for global health. Modern methods of therapy do not completely eliminate HBV …

Viruses hijack host cellular receptors and functions for replication, thereby posing a
complication in identifying therapeutic targets. The CRISPR/Cas 9 platform has …

Hepatitis B virus (HBV) infection remains a global health challenge. Despite the availability
of effective preventive vaccines, millions of people are at risk of cirrhosis and hepatocellular …

Clustered regularly interspaced short palindromic repeats (CRISPR) systems are a set of
versatile gene-editing toolkit that perform diverse revolutionary functions in various fields of …

As CRISPR/Cas systems have been refined over time, there has been an effort to apply
them to real world problems, such as developing sequence-targeted antiviral therapies …