Leprosy is an infectious disease caused by non‐cultivable bacteria Mycobacterium leprae.
Th17 cells play vital roles during pathogenesis of leprosy reactions and IL‐23 is involved in …

Th17 cells play vital role during pathogenesis of leprosy reactions. Previously, we have
reported that IL-23 is involved in Th17 cells differentiation. Subsequently, our group also …

Leprosy type 1 reaction (T1R) is a cell-mediated inflammatory reaction which involves skin
and peripheral nerves in leprosy. Lesions with T1R have higher production of IL-17 cytokine …

Mycobacterium leprae is a kind of disease-causing bacteria and results in leprosy in human.
Gamma delta (γδ) T cell is a T-cell subset that is presented in both human dermis and …

Interleukin-17A (IL-17A) is a proinflamatory cytokine that plays an important role in fighting
pathogens at mucosal interfaces, by summoning neutrophils and upregulating cytoplasmatic …

Abstract Type 1 reactions (T1R) an inflammatory condition, of local skin patches in 30–40%
leprosy patients during the course of MDT. IL-17A and IL-17F play an important role in …

The generation of cell-mediated immunity against intracellular infection involves the
production of IL-12, a critical cytokine required for the development of Th1 responses. The …

Psoriasis is a chronic skin disease resulting from the dysregulated interplay between
keratinocytes and infiltrating immune cells. We report on a psoriasis-like disease model …

Background Patients with localized tuberculoid and generalized lepromatous leprosy show
respectively Th1 and Th2 cytokine profile. Additionally, other patients in both types of leprosy …

Leprosy reactional episodes are acute inflammatory events that may occur during the
clinical course of the disease. Type 1 reaction (T1R) is associated with an increase in neural …