In the past two decades, much evidence has accumulated unequivocally demonstrating that
child abuse and neglect is associated with a marked increase in risk for major psychiatric …

More than 3 decades ago, our group and others1, 2 suggested, based on results from
laboratory animal studies, that trauma early in life in the form of child abuse and/or neglect …

The neurobiological mechanisms by which childhood maltreatment heightens vulnerability
to psychopathology remain poorly understood. It is likely that a complex interaction between …

Exposure to interpersonal violence or abuse affects the physical and emotional well-being of
affected individuals. In particular, exposure to trauma during development increases the risk …

A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Affect dysregulation, defined as the impaired ability to regulate or tolerate negative
emotional states, has been associated with interpersonal trauma and posttraumatic stress …

Each year within the US alone over 770,000 children are victimized by abuse and neglect
(US Department of Health and Human Services, 2010), and this figure is likely to …

Childhood maltreatment represents a significant risk factor for psychopathology. Recent
research has begun to examine both the functional and structural neurobiological correlates …

Childhood abuse is associated with later psychopathology, including conduct disorder,
antisocial personality disorder, anxiety and depression as well as a heightened risk of health …

Recent studies have provided robust evidence for an association between childhood trauma
(CT) and psychosis. Meta-analyses have quantified the association, pointing to odds ratios …