Background Unwarranted administration of antibiotics in acute pancreatitis presents a global
challenge. The clinical reasoning behind the misuse is poorly understood. Our aim was to …

Introduction Practice guidelines for the management of acute pancreatitis make
recommendations in relation to antibiotic prophylaxis and treatment in acute pancreatitis …

Acute pancreatitis is a complex inflammatory disease with significant morbidity and mortality.
Despite advances in its management, the role of antibiotics in the prophylaxis and treatment …

In an attempt to decrease the infectious complications of acute pancreatitis and its high
mortality, many investigators have conducted randomized prospective trials on the efficacy …

Background Differentiating inflammation from bacterial infection in patients with acute
pancreatitis can be difficult. Procalcitonin can distinguish infection from inflammation, and …

Bacterial infection of pancreatic necrotic tissue is a frequent complication of severe acute
pancreatitis. Infected pancreatic necrotic tissue is observed in 30–70% of all patients …

Background: The effectiveness of prophylactic antibiotics in severe acute pancreatitis (SAP)
remains a debatable issue. This meta-analysis aimed to determine the efficacy of …

INTRODUCTION The development of pancreatic infection is associated with the
development of a deteriorating disease with subsequent high morbidity and mortality. There …

Background: Recent evidence has shown that prophylactic antibiotic treatment in patients
with acute pancreatitis is not associated with a significant decrease in mortality or morbidity …

(AGA) on the initial management of acute pancreatitis (AP). The guideline was developed by
the AGA's Clinical Practice Guideline Committee and approved by the AGA Governing …