Psychiatric disorders are highly genetically correlated, but little research has been
conducted on the genetic differences between disorders. We developed a new method …

Objective: The authors conducted a review of the history and empirical basis of genomewide
association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date …

Most psychiatric disorders are moderately to highly heritable. The degree to which genetic
variation is unique to individual disorders or shared across disorders is unclear. To examine …

Substantial genetic liability is shared across psychiatric disorders but less is known about
risk variants that are specific to a given disorder. We used multi-trait conditional and joint …

Although genome-wide association studies (GWAS), in general, facilitated important
discovery of new biological knowledge about diseases, 1--3 identified variants for …

Many gene-based association tests have been proposed for genomewide association
studies (GWAS). However, the power of existing gene-based tests is... Genome-wide …

Genome-wide association studies (GWAS) have yielded a plethora of new findings in the
past 3 years. By early 2009, GWAS on 47 samples of subjects with attention-deficit …

Schizophrenia is a complex disorder caused by both genetic and environmental factors.
Using 9,087 affected individuals, 12,171 controls and 915,354 imputed SNPs from the …

A common belief among statistical geneticists is that genomewide association studies
1(GWAS) rendered candidate gene studies 2 obsolete. It is also widely believed that nearly …

Psychiatric diseases are of major public health importance owing to their enormous
morbidity, mortality and personal/societal cost. Little is known for certain about the etiology of …