This protocol details a rapid and reliable method for the production and titration of high-titre
viral pseudotype particles with the SARS-CoV-2 spike protein (and D614G or other variants …

This protocol details a rapid and reliable method for the production and titration of high-titer
viral pseudotype particles with the SARS-CoV-2 spike protein (and D614G variant) on a …

Virus neutralization assay is principally conducted by measuring the ability of the antibodies
in patient sera to prevent the infection of susceptible cells by the virus. As SARS-CoV-2 is …

The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus requires reliable assays
for studying viral entry mechanisms which remains poorly understood. This knowledge is …

In this study, we showed that a codon optimized version of the spike (S) protein of SARS-
CoV-2 can migrate to the cell membrane. However, efficient production of Moloney murine …

Working with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is restricted to
biosafety level III (BSL-3) laboratory. The study used a trans-complementation system …

The severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) Spike glycoprotein is
solely responsible for binding to the host cell receptor and facilitating fusion between the …

Pseuodotyped particles have significant importance and use in virology as tools for studying
the biology of highly pathogenic viruses in a lower biosafety environment. The biological …

COVID-19 is an ongoing pandemic caused by the highly infectious coronavirus SARS-CoV-
2 that is engaging worldwide scientific research to find a timely and effective eradication …

The protocol outlined represents a cost-effective, rapid and reliable method for the
generation of high-titre viral pseudotype particles with the wild-type SARS-CoV spike protein …