Differentially expressed mRNA targets of differentially expressed miRNAs predict changes in the TP53 axis and carcinogenesis-related pathways in human …
L Al-Eryani, S Waigel, A Tyagi, J Peremarti… - Toxicological …, 2018 - academic.oup.com
Arsenic is a widely distributed toxic natural element. Chronic arsenic ingestion causes
several cancers, especially skin cancer. Arsenic-induced cancer mechanisms are not well …
several cancers, especially skin cancer. Arsenic-induced cancer mechanisms are not well …
Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of …
M Banerjee, A Ferragut Cardoso, L Al-Eryani, J Pan… - Archives of …, 2021 - Springer
Chronic arsenic exposure causes skin cancer, although the underlying molecular
mechanisms are not well defined. Altered microRNA and mRNA expression likely play a …
mechanisms are not well defined. Altered microRNA and mRNA expression likely play a …
Cell cycle pathway dysregulation in human keratinocytes during chronic exposure to low arsenite
L Al-Eryani, S Waigel, V Jala, SF Jenkins… - Toxicology and applied …, 2017 - Elsevier
Background Arsenic is naturally prevalent in the earth's crust and widely distributed in air
and water. Chronic low arsenic exposure is associated with several cancers in vivo …
and water. Chronic low arsenic exposure is associated with several cancers in vivo …
Aberrantly expressed genes in HaCaT keratinocytes chronically exposed to arsenic trioxide
Inorganic arsenic is a known environmental toxicant and carcinogen of global public health
concern. Arsenic is genotoxic and cytotoxic to human keratinocytes. However, the biological …
concern. Arsenic is genotoxic and cytotoxic to human keratinocytes. However, the biological …
SILAC‐based quantitative proteomic analysis reveals widespread molecular alterations in human skin keratinocytes upon chronic arsenic exposure
Chronic exposure to arsenic is associated with dermatological and nondermatological
disorders. Consumption of arsenic‐contaminated drinking water results in accumulation of …
disorders. Consumption of arsenic‐contaminated drinking water results in accumulation of …
Arsenic-exposed keratinocytes exhibit differential microRNAs expression profile; potential implication of miR-21, miR-200a and miR-141 in melanoma pathway
H Gonzalez, C Lema, RA Kirken… - Clinical cancer …, 2015 - ingentaconnect.com
Background: Long-term exposure to arsenic has been linked to cancer in different organs
and tissues, including skin. Methods: Here, non-malignant human keratinocytes (HaCaT) …
and tissues, including skin. Methods: Here, non-malignant human keratinocytes (HaCaT) …
MiR-96-5p Suppresses Progression of Arsenite-Induced Human Keratinocyte Proliferation and Malignant Transformation by Targeting Denticleless E3 Ubiquitin …
Y Li, Q Zhao, J Yao, C Lv, Y Gao, D Sun, Y Yang - Toxics, 2023 - mdpi.com
Long-term exposure to arsenic has been linked to a variety of cancers, among which skin
cancer is the most prevalent form. However, the mechanism underlying arsenic …
cancer is the most prevalent form. However, the mechanism underlying arsenic …
[HTML][HTML] Integration of microRNAome, proteomics and metabolomics to analyze arsenic-induced malignant cell transformation
Y Zhou, Y Wang, J Su, Z Wu, C Wang, W Zhong, X Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Long-term exposure to arsenic has been linked to tumorigenesis in different organs and
tissues, such as skin; however, the detailed mechanism remains unclear. In this present …
tissues, such as skin; however, the detailed mechanism remains unclear. In this present …
Delineating the effects of passaging and exposure in a longitudinal study of arsenic-induced squamous cell carcinoma in a HaCaT cell line model
Cutaneous squamous cell carcinoma (cSCC) is a major deleterious health effect of chronic
arsenic (iAs) exposure. The molecular mechanism of arsenic-induced cSCC remains poorly …
arsenic (iAs) exposure. The molecular mechanism of arsenic-induced cSCC remains poorly …
miRNA expression profiles of premalignant and malignant arsenic-induced skin lesions
L Al-Eryani, SF Jenkins, VA States, J Pan, JC Malone… - PloS one, 2018 - journals.plos.org
Arsenic, a naturally occurring element, contaminates the drinking water of over 200 million
people globally. Chronic arsenic exposure causes multiple cancers including those …
people globally. Chronic arsenic exposure causes multiple cancers including those …