People worldwide are living longer, and it is estimated that by 2050, the proportion of the
world's population over 60 years of age will nearly double. Natural lung aging is associated …

Lung aging is associated with structural remodeling, a decline of respiratory function and a
higher susceptibility to acute and chronic lung diseases. Individual factors that modulate …

Age is a major risk factor for chronic respiratory diseases such as idiopathic pulmonary
fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and certain phenotypes of …

The prevalence of lung conditions, such as COPD and pulmonary fibrosis, and lung
infections, such as pneumonia, increases sharply with age. The physiologic, cellular, and …

The population is aging at a rate never seen before in human history. As the number of
elderly adults grows, it is imperative we expand our understanding of the underpinnings of …

Natural lung aging is marked by molecular changes that occur during development,
maturation, and late-life decline. At the cellular and whole organ level, degenerative …

Advancing age is associated with a decline in the integrity of physical barriers and protection
against invading pathogens, and age-related changes in the immune system are associated …

The global population is aging with significant gains in life expectancy particularly in the
developed world. Consequently, greater focus on understanding the processes that underlie …

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the
lungs that usually manifests late in life. Physiologic and immunologic changes that occur in …

Pulmonary fibrosis is a chronic and fatal lung disease that significantly impacts the aging
population globally. To date, anti-fibrotic, immunosuppressive, and other adjunct therapy …