The adverse outcome pathway framework applied to neurological symptoms of COVID-19

HT Hogberg, A Lam, E Ohayon, MA Shahbaz… - Cells, 2022 - mdpi.com
Several reports have shown that the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has the potential to also be neurotropic. However, the mechanisms by which …

[HTML][HTML] Neurological sequela and disruption of neuron-glia homeostasis in SARS-CoV-2 infection

MG Savelieff, EL Feldman, AM Stino - Neurobiology of disease, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic is responsible for 267 million
infections and over 5 million deaths globally. COVID-19 is caused by severe acute …

Neurological consequences of SARS-CoV-2 infection and concurrence of treatment-induced neuropsychiatric adverse events in COVID-19 patients: navigating the …

P Borah, PK Deb, B Chandrasekaran… - Frontiers in molecular …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the angiotensin-
converting enzyme 2 (ACE2) receptor and invade the human cells to cause COVID-19 …

Neuroinflammation and Its Impact on the Pathogenesis of COVID-19

MM Almutairi, F Sivandzade, TH Albekairi… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical manifestations of COVID-19 …

Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection

M Pacheco-Herrero, LO Soto-Rojas… - Frontiers in …, 2021 - frontiersin.org
The current pandemic caused by the new severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a public health emergency. To date, March 1, 2021, coronavirus …

Multiple neuroinvasive pathways in COVID-19

D Bougakov, K Podell, E Goldberg - Molecular neurobiology, 2021 - Springer
COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2.
While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on …

Pathophysiological clues to how the emergent SARS-CoV-2 can potentially increase the susceptibility to neurodegeneration

M Dolatshahi, M Sabahi, MH Aarabi - Molecular neurobiology, 2021 - Springer
Along with emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) in late 2019, a myriad of neurologic symptoms, associated with structural brain …

[HTML][HTML] COVID-19 through adverse outcome pathways: Building networks to better understand the disease–3rd CIAO AOP design workshop

LA Clerbaux, N Amigó, MJ Amorim, A Bal-Price… - Altex, 2022 - ncbi.nlm.nih.gov
Abstract On April 28–29, 2021, 50 scientists from different fields of expertise met for the 3 rd
online CIAO workshop. The CIAO project “Modelling the Pathogenesis of COVID-19 using …

COVID-19-associated neurological disorders: the potential route of CNS invasion and blood-brain barrier relevance

A Achar, C Ghosh - Cells, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human
coronavirus that has sparked a global pandemic of the coronavirus disease of 2019 (COVID …

Neurological manifestations of COVID-19: available evidences and a new paradigm

F Khatoon, K Prasad, V Kumar - Journal of neurovirology, 2020 - Springer
The recent pandemic outbreak of coronavirus is pathogenic and a highly transmittable viral
infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2). In …