F Saponaro, G Rutigliano, S Sestito… - Frontiers in Molecular …, 2020 - frontiersin.org
Angiotensin-converting enzyme 2 (ACE2) is related to ACE but turned out to counteract several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …
G Li, X He, L Zhang, Q Ran, J Wang, A Xiong… - Journal of …, 2020 - Elsevier
It has been reported that SARS-CoV-2 may use ACE2 as a receptor to gain entry into human cells, in a way similar to that of SARS-CoV. Analyzing the distribution and expression level of …
LI Labzin, KY Chew, K Eschke, X Wang, T Esposito… - Science …, 2023 - science.org
Macrophages are key cellular contributors to the pathogenesis of COVID-19, the disease caused by the virus SARS-CoV-2. The SARS-CoV-2 entry receptor ACE2 is present only on …
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have triggered global pandemic that continue to impact adversely human health. New …
SM Gonzalez, AB Siddik, RC Su - Frontiers in Immunology, 2021 - frontiersin.org
Since being identified as a key receptor for SARS-CoV-2, Angiotensin converting enzyme 2 (ACE2) has been studied as one of the potential targets for the development of preventative …
Y Lu, Q Zhu, DM Fox, C Gao, SA Stanley… - Molecular Biology of …, 2022 - Am Soc Cell Biol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes its Spike (S) glycoprotein to bind to the angiotensin-converting enzyme 2 (ACE2) receptor for cellular …
X Song, W Hu, H Yu, L Zhao, Y Zhao, Y Zhao - bioRxiv, 2020 - biorxiv.org
Abstract Angiotensin-converting enzyme-2 (ACE2) has been recognized as the binding receptor for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that infects …
A Onnis, E Andreano, C Cassioli, F Finetti… - Journal of Experimental …, 2022 - rupress.org
CTL-mediated killing of virally infected or malignant cells is orchestrated at the immune synapse (IS). We hypothesized that SARS-CoV-2 may target lytic IS assembly to escape …
SARS-CoV-2 triggered the most severe pandemic of recent times. To enter into a host cell, SARS-CoV-2 binds to the angiotensin-converting enzyme 2 (ACE2). However, subsequent …