[HTML][HTML] Combination regimen of nirmatrelvir/ritonavir and molnupiravir for the treatment of persistent SARS-CoV-2 infection: A case report and a scoping review of the …

D Marangoni, RM Antonello, M Coppi… - International Journal of …, 2023 - Elsevier
Immunocompromised patients still experience unpredictable courses of COVID-19, despite
that effective vaccines and drugs against SARS-CoV-2 are now available. Antiviral …

Successful treatment of persisting SARS-CoV-2 infection in an immunocompromised patient with repeated nirmatrelvir/ritonavir courses: a case report

AL Lindahl, MJ Ahava, M Haukipää, HR Kreivi… - Infectious …, 2023 - Taylor & Francis
Background In immunocompromised patients, persistent SARS-CoV-2 viral shedding and
relapsing COVID-19 pneumonia have been described. Currently, little is known about the …

Successful treatment of persistent SARS-CoV-2 infection with nirmatrelvir/ritonavir plus sotrovimab in four immunocompromised patients

M Lanzafame, M Gottardi, L Guella, L Collini… - Journal of …, 2023 - Taylor & Francis
Immunocompromised patients with leukemia/lymphoma often have a suboptimal response
to vaccination against SARS-CoV-2 and, if infected, can develop a persistent infection …

Oral Molnupiravir and Nirmatrelvir/Ritonavir for the Treatment of COVID-19: A Literature Review with a Focus on Real-World Evidence

I Karniadakis, N Mazonakis, C Tsioutis… - Infectious Disease …, 2023 - mdpi.com
Vaccines remain the cornerstone of medical prevention and are highly effective in reducing
the risk of severe disease and death due to coronavirus disease 2019 (COVID-19). In the …

Case report: Sotrovimab, remdesivir and nirmatrelvir/ritonavir combination as salvage treatment option in two immunocompromised patients hospitalized for COVID-19

F Baldi, C Dentone, M Mikulska, D Fenoglio… - Frontiers in …, 2023 - frontiersin.org
COVID-19 in immunocompromised patients is difficult to treat. SARS-CoV-2 interaction with
the host immune system and the role of therapy still remains only partly understood. There …

Dual combined antiviral treatment with remdesivir and nirmatrelvir/ritonavir in patients with impaired humoral immunity and persistent SARS‐CoV‐2 infection

Z Pasquini, A Toschi, B Casadei… - Hematological …, 2023 - Wiley Online Library
Despite global vaccination efforts, immunocompromized patients remain at high risk for
COVID‐19‐associated morbidity. In particular, patients with impaired humoral immunity …

Comparative efficacy and safety of nirmatrelvir/ritonavir and molnupiravir for COVID‐19: A systematic review and meta‐analysis

B Amani, A Akbarzadeh, B Amani… - Journal of Medical …, 2023 - Wiley Online Library
This study aimed to compare the efficacy and safety of nirmatrelvir/ritonavir (Paxlovid) with
molnupiravir in the treatment of coronavirus disease 2019 (COVID‐19). To end this …

Coronavirus disease 2019 rebounds following nirmatrelvir/ritonavir treatment

CC Lai, PR Hsueh - Journal of Medical Virology, 2023 - Wiley Online Library
Abstract Nirmatrelvir/ritonavir (NMV‐r) is an effective anti‐SARS‐CoV‐2 agent and has been
recommended in the treatment of nonhospitalized patients with COVID‐19. In rare …

Optimizing COVID-19 treatment in immunocompromised patients: early combination therapy with remdesivir, nirmatrelvir/ritonavir and sotrovimab

I Gentile, M Foggia, M Silvitelli, A Sardanelli… - Virology Journal, 2023 - Springer
Background Morbidity and mortality are higher in immunocompromised patients affected by
COVID-19 than in the general population. Some authors have successfully used antiviral …

[HTML][HTML] The use of nirmatrelvir-ritonavir in a case of breakthrough long COVID

LN Geng, HF Bonilla, RW Shafer… - … and Hypothesis in …, 2023 - xiahepublishing.com
Post-acute sequelae of SARS-CoV-2 (PASC) or long COVID is a major public health
problem. The underlying mechanism (s) of this disease remains unclear, and there is a lack …