Purpose: Tumor-initiating cells are resistant to chemotherapy, but how microRNAs play a
role in regulating drug resistance of breast tumor–initiating cells (BT-IC) needs to be …

Background Chemotherapy is an important component in the treatment paradigm for breast
cancers. However, the resistance of cancer cells to chemotherapeutic agents frequently …

Acquired resistance to classical chemotherapeutics is a major obstacle in cancer treatment.
Doxorubicin is frequently used in breast cancer therapy either as single-agent or in …

MicroRNAs are emerging as critical regulators of the initiation and progression of multiple
types of human cancers, including breast cancer. In the present study, the expression of miR …

MicroRNAs (miRNAs) are a class of naturally occurring, small, non-coding RNAs which play
important roles in diverse biological processes and are acting as key regulators of …

Breast cancer is the most common malignancy in women all over the world. MiRNAs are a
type of small noncoding RNA that can regulate various cellular processes via binding …

Breast cancer is a serious health problem worldwide. Acquisition of multi-drug resistance
(MDR) during the treatment of breast cancer is still considered a major clinical obstacle …

Drug resistance remains a major problem in the treatment of conventional chemotherapeutic
agents in breast cancers. Owing to heterogeneity and complexity of chemoresistance …

Radiotherapy resistance remains a major obstacle for patients with breast cancer. miRNAs
are important regulators in many biological processes including proliferation, apoptosis …

MicroRNAs (miRNAs) have critical roles in regulating cancer cell survival, proliferation and
sensitivity to chemotherapy. The potential application of using miRNAs to predict …