Despite major therapeutic advances in the management of patients with breast cancer,
central nervous system (CNS) metastases remain an intractable problem, particularly in …

As systemic therapy of metastatic breast cancer improves, CNS involvement is becoming a
more widespread problem. This article summarizes the current knowledge regarding the …

Brain metastases (BMs) are an important source of morbidity and mortality in patients with
metastatic breast cancer (BC). As survival of patients with advanced BC considerably …

Remarkable progress in breast cancer treatment has improved patient survival, resulting in
an increased incidence of brain metastasis (BM). Current treatment options for BM are …

Brain metastasis is an end stage in breast cancer progression. Traditional treatment options
have minimal efficacy, and overall survival is on the order of months. The incidence of brain …

It is estimated that 10% to 30% of patients with solid tumors are diagnosed with central
nervous system (CNS) metastasis. Common primary sites include lung, breast, melanoma …

One of the most feared sequelae after a diagnosis of advanced breast cancer is
development of metastases to the brain as this diagnosis can affect physical function …

Simple Summary In this review, we present the latest information on the pathophysiology,
diagnosis, and local and systemic treatment of brain metastases from breast cancer, with a …

Clinically symptomatic metastases to the central nervous system (CNS) occur in∼ 10 to 15%
of patients with metastatic beast cancer. CNS metastases are traditionally viewed as a late …

Abstract Between 100,000 and 170,000 patients with cancer develop central nervous
system (CNS) metastases each year in the US, of which∼ 20% carry a primary diagnosis of …