Background Non-small cell lung cancer (NSCLC) accounts for the vast majority of lung
cancers. Early detection is crucial to reduce lung cancer-related mortality. Aberrant DNA …

Aberrant DNA methylation is a commonly observed epigenetic change in lung cancer.
Folate has been suggested to play a role in the homeostasis of DNA methylation and has …

Background The death rate of lung cancer (LC) ranks first in the world. Changes of DNA
methylation in peripheral blood may be related to malignant tumors. It is necessary to …

Background Lung cancer (LC) is the leading cause of cancer-related morbidity and mortality
in China. Exploring novel biomarkers for the early detection of LC is important. Materials and …

Lung cancer remains a global health problem with a high mortality rate. CpG island
methylation is a common aberration frequently associated with gene silencing in multiple …

Background: Lung cancer is the leading cause of cancer-related deaths worldwide due
mainly to late diagnosis and poor prognosis. Aberrant promoter methylation is an important …

Early detection of lung cancer (LC) is vital for reducing LC-related mortality. However,
noninvasive diagnostic tools remain a great challenge. We aim to identify blood-based …

DNA methylation has been reported to become a potential powerful tool for cancer detection
and diagnosis. However, the possibilities for the application of blood-based gene …

The global increase in lung cancer burden, together with its poor survival and resistance to
classical chemotherapy, underscores the need for identification of critical molecular events …

Background: Global DNA hypomethylation is an early molecular event in carcinogenesis.
Whether methylation measured in peripheral blood mononuclear cells (PBMCs) DNA is a …