J Lu, G Xie, W Jia, W Jia - Frontiers of medicine, 2013 - Springer
Insulin resistance (IR) is a key pathological feature of metabolic syndrome and subsequently causes serious health problems with an increased risk of several common metabolic …
MM Adeva, J Calviño, G Souto, C Donapetry - Amino acids, 2012 - Springer
Peripheral resistance to insulin action is the major mechanism causing the metabolic syndrome and eventually type 2 diabetes mellitus. The metabolic derangement associated …
Abstract Purpose of Review Elevations in circulating branched chain amino acids (BCAAs) have gained attention as potential contributors to the development of insulin resistance and …
E Supruniuk, E Żebrowska… - Critical Reviews in Food …, 2023 - Taylor & Francis
Branched chain amino acids (BCAA) and their derivatives are bioactive molecules with pleiotropic functions in the human body. Elevated fasting blood BCAA concentrations are …
Dysregulation of insulin action is most often considered in the context of impaired glucose homeostasis, with the defining feature of diabetes mellitus being elevated blood glucose …
M Holeček - Nutrition & metabolism, 2018 - Springer
Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are essential amino acids with protein anabolic properties, which have been studied in a number of muscle …
A Rietman, J Schwarz, D Tomé, FJ Kok… - European journal of …, 2014 - nature.com
Dietary proteins have an insulinotropic effect and thus promote insulin secretion, which indeed leads to enhanced glucose clearance from the blood. In the long term, however, a …
Z Bloomgarden - Journal of diabetes, 2018 - europepmc.org
Branched-chain amino acids (BCAA) have increasingly been studied as playing a role in diabetes, with the PubMed search string" diabetes" AND" branched chain amino acids" …
R Liu, H Li, W Fan, Q Jin, T Chao, Y Wu, J Huang… - Nutrients, 2017 - mdpi.com
The available findings concerning the association between branched-chain amino acids (BCAAs)—particularly leucine—and insulin resistance are conflicting. BCAAs have been …