Abstract Background and Hypothesis Schizophrenia has been robustly associated with
multiple genetic and environmental risk factors. Childhood adversity is one of the most …

A history of childhood adversity is associated with psychotic disorder, with an increase in risk
according to number or severity of exposures. However, it is not known why only some …

Background A history of childhood adversity is associated with psychotic disorder, with an
increase in risk according to the number of exposures. However, it is not known why only …

Abstract Objectives The familial (“genetic”) high-risk (FHR) paradigm enables assessment of
individuals at risk for schizophrenia based on a positive family history of schizophrenia in …

BackgroundChildhood adversity is a putative risk factor for schizophrenia, although
evidence supporting this suggestion is inconsistent and controversial. The aim of this review …

BackgroundThere is a wealth of literature on the observed association between childhood
trauma and psychotic illness. However, the relationship between childhood trauma and …

Schizophrenia is a heritable complex phenotype associated with a background risk
involving multiple common genetic variants of small effect and a multitude of environmental …

BackgroundAssociations of socioenvironmental features like urbanicity and neighborhood
deprivation with psychosis are well-established. An enduring question, however, is whether …

Recent evidence shows that genetic and environmental risk factors for psychotic disorders
are associated with higher levels of schizotypy (or psychosis proneness) in the general …

Background Several nonpsychotic psychiatric disorders in childhood and adolescence can
precede the onset of schizophrenia, but the etiology of this relationship remains unclear. We …