Human fibroblast growth factor-treated adipose-derived stem cells facilitate wound healing and revascularization in rats with streptozotocin-induced diabetes mellitus

SY Chang, JH Lee, SC Oh, MY Lee, NK Lim - Cells, 2023 - mdpi.com
Diabetes mellitus contributes to 15–25% of all chronic foot ulcers. Peripheral vascular
disease is a cause of ischemic ulcers and exacerbates diabetic foot disease. Cell-based …

Adipose-derived stem cells accelerate diabetic wound healing through the induction of autocrine and paracrine effects

YR Kuo, CT Wang, JT Cheng, GS Kao… - Cell …, 2016 - journals.sagepub.com
Cell-based therapy is an attractive approach for the treatment of chronic nonhealing
wounds. This study investigated whether adipose-derived stem cells (ASCs) can accelerate …

Adipose stem cells isolated from diabetic mice improve cutaneous wound healing in streptozotocin-induced diabetic mice

R An, Y Zhang, Y Qiao, L Song, H Wang… - Stem Cell Research & …, 2020 - Springer
Background Adipose-derived mesenchymal stem cells (ASCs) therapy is emerging as a
novel therapeutic option for the treatment of a variety of diseases including diabetes and …

Diabetes impairs adipose tissue–derived stem cell function and efficiency in promoting wound healing

F Cianfarani, G Toietta, G Di Rocco… - Wound repair and …, 2013 - Wiley Online Library
Adipose tissue–derived stem cells (ASC s) are gaining increasing consideration in tissue
repair therapeutic application. Recent evidence indicates that ASC s enhance skin repair in …

Locally administered adipose-derived stem cells accelerate wound healing through differentiation and vasculogenesis

C Nie, D Yang, J Xu, Z Si, X Jin… - Cell …, 2011 - journals.sagepub.com
Despite advances in wound closure techniques and devices, there is still a critical need for
new methods of enhancing the healing process to achieve optimal outcomes. Recently …

Adipose-derived stem cells combined with platelet-rich plasma enhance wound healing in a rat model of full-thickness skin defects

X Ni, X Shan, L Xu, W Yu, M Zhang, C Lei, N Xu… - Stem cell research & …, 2021 - Springer
Background Wound healing is impaired in patients with diabetes due to the multifactorial
etiology of the disease, which limits the therapeutic efficacy of various approaches. This …

Low-glucose culture environment can enhance the wound healing capability of diabetic adipose-derived stem cells

CW Li, TH Young, MH Wang, MY Pei, TY Hsieh… - Stem Cell Research & …, 2023 - Springer
Background Application of autologous adipose-derived stem cells (ASC) for diabetic chronic
wounds has become an emerging treatment option. However, ASCs from diabetic …

Adipose-derived mesenchymal stem cells in the treatment of diabetic foot ulcers: a review of preclinical and clinical studies

FJ Álvaro-Afonso, I Sanz-Corbalán… - …, 2020 - journals.sagepub.com
This review provides an outline of the use of adipose-derived mesenchymal stem cells
(AMSCs) in the treatment of diabetic foot ulcers (DFUs). A systematic search of PubMed and …

[HTML][HTML] Adipose-derived stem cells: effectiveness and advances in delivery in diabetic wound healing

M Gadelkarim, AI Abushouk, E Ghanem… - Biomedicine & …, 2018 - Elsevier
With the increasing global prevalence of diabetes mellitus, a significant rise in the number of
patients suffering from non-healing wounds is expected. However, available treatments …

Injection of stem cells derived from allogeneic adipose tissue, a new strategy for the treatment of diabetic wounds

R Izadi, SH Hejazi, S Bahramikia - Journal of Diabetes and its …, 2023 - Elsevier
A diabetic wound is one of the major complications of Diabetes mellitus. Considering the
impact of these wounds on the health and quality of life of diabetic patients, the need for a …